Evidence map›Paper›PMID 30303408›Full record

ArticleAmerican journal of respiratory and critical care medicine2019

Development and Preliminary Validation of the Lung Transplant Quality of Life (LT-QOL) Survey.

Jonathan P Singer, Allison Soong, Joan Chen, Pavan Shrestha, Hanjing Zhuo, Ying Gao, John R Greenland, Steven R Hays, Jasleen Kukreja, Jeffrey Golden and 2 more

Abstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Timing of quality of life and lung function changes during the first year following lung transplantation: A multicenter prospective cohort study.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2026
    Observational
  6. Article
  7. Post-lung transplant surveillance in 2026: current practice, variability, and the need for standardization.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Review
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Changes in the health-related quality of life and social reintegration status after lung transplantation following hematopoietic stem cell transplantation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  18. Use of Wearables and Implantable Devices to Monitor Pulmonary Health in the Outpatient Setting.American journal of respiratory and critical care medicine · 2022
    Article
  19. The role of palliative care in lung transplantation.Journal of thoracic disease · 2021
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Jonathan P Singer1 Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine.ORCID 0000-0003-0224-7472
Allison Soong1 Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine.
Joan Chen1 Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine.
Pavan Shrestha1 Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine.
Hanjing Zhuo1 Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine.
Ying Gao1 Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine.
John R Greenland1 Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine.
Steven R Hays1 Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine.
Jasleen Kukreja2 Division of Cardiothoracic Surgery.
Jeffrey Golden1 Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine.
Steven E Gregorich3 Department of Medicine, and.
Anita L Stewart4 Institute for Health & Aging, University of California, San Francisco, San Francisco, California.
University of California, San Francisco · US

Funding

RESOURCE CENTER FOR AGING RESEARCH IN DIVERSE POPULATIONP30AG015272 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LEAH S KARLINER · 1997 to 2026
$19.5M
Frailty and patient centered outcomes in candidates for lung transplantationR01HL134851 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SINGER, JONATHAN PAUL · 2017 to 2021
$3.4M
The Effects of Lung Transplant on Disability and Health-Related Quality of LifeK23HL111115 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SINGER, JONATHAN PAUL · 2012 to 2016
$832k
Immune Mechanisms of Large-airway Lymphocytic BronchitisIK2CX001034 · VA · VETERANS AFFAIRS MED CTR SAN FRANCISCO · PI GREENLAND, JOHN · 2015 to 2019
–
CSRD VA IK2 CX001034NHLBI NIH HHS K23 HL111115NHLBI NIH HHS R01 HL134851NIA NIH HHS P30 AG015272
6 · The paper itself

Abstract

rationaleAlthough lung transplantation aims to improve health-related quality of life (HRQL), existing instruments fail to include health domains considered important in this population.

objectivesWe aimed to develop a comprehensive lung transplant-specific instrument to address this shortcoming.

methodsWe developed a pool of 126 candidate items addressing domains previously identified as important by lung transplant recipients. Through cognitive interviews conducted in 43 transplant recipients, items deemed irrelevant or redundant were dropped. The 84 remaining items were field tested in lung transplant recipients. Exploratory and confirmatory factor analyses were used to evaluate the factor structure, and scales were evaluated for internal consistency and construct validity. MEASUREMENTS AND MAIN

resultsThe 84-item preliminary survey was administered to 201 lung transplant recipients with a mean age of 57.9 (±12.7) years; 46% were female. After factor analyses and internal consistency evaluation, we retained 60 items comprising the Lung Transplant Quality of Life (LT-QOL) Survey. The LT-QOL contains 10 scales that measure symptoms, health perceptions, functioning, and well-being. The confirmatory factor analysis model had good approximate fit (comparative fit index = 0.990; standardized root-mean-square residual = 0.062). Cronbach αs for the 10 scales ranged from 0.75 to 0.95. Interscale correlations were consistent with hypothesized relationships. Subjects with severe chronic lung allograft dysfunction (n = 13) reported significantly worse HRQL than subjects without chronic lung allograft dysfunction (n = 168) on 6 of the 10 LT-QOL scales.

conclusionsThe LT-QOL is a new, multidimensional instrument that characterizes and quantifies HRQL in lung transplant recipients.

Indexed as

Lung TransplantationQuality of LifeAdultAgedFemaleHumansMaleMiddle AgedReproducibility of ResultsSurveys and QuestionnairesYoung Adultdisabilityhealth-related quality of lifelung transplantationpatient-centered outcomes

Identifiers

PMID30303408
PMCPMC6467318
OpenAlexW2901328144

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.