Evidence map›Paper›PMID 30303379›Full record

ArticleJournal of the American Chemical Society2018

Ti-Catalyzed Radical Alkylation of Secondary and Tertiary Alkyl Chlorides Using Michael Acceptors.

Xiangyu Wu, Wei Hao, Ke-Yin Ye, Binyang Jiang, Gisselle Pombar, Zhidong Song, Song Lin

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Article
  2. Titanium-Catalyzed Diastereoselective Keto- and Iminonitrile Cyclizations.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Total synthesis and biological activity of "carbamorphine": O-to-CHProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
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  16. Article
  17. Article
  18. Article
  19. C(spChemical science · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiangyu WuDepartment of Chemistry and Chemical Biology , Cornell University , Ithaca , New York 14853 , United States.
Wei HaoDepartment of Chemistry and Chemical Biology , Cornell University , Ithaca , New York 14853 , United States.
Ke-Yin YeDepartment of Chemistry and Chemical Biology , Cornell University , Ithaca , New York 14853 , United States.
Binyang JiangDepartment of Chemistry and Chemical Biology , Cornell University , Ithaca , New York 14853 , United States.
Gisselle PombarDepartment of Chemistry and Chemical Biology , Cornell University , Ithaca , New York 14853 , United States.
Zhidong SongDepartment of Chemistry and Chemical Biology , Cornell University , Ithaca , New York 14853 , United States.
Song LinDepartment of Chemistry and Chemical Biology , Cornell University , Ithaca , New York 14853 , United States.ORCID 0000-0002-8880-6476

Funding

TR&D 4 for ACERT, 2017-2021 funding periodP41GM103521 · NIGMS · CORNELL UNIVERSITY · PI FREED, JACK H · 2012 to 2021
$11.7M
NIGMS NIH HHS P41 GM103521
6 · The paper itself

Abstract

Alkyl chlorides are common functional groups in synthetic organic chemistry. However, the engagement of unactivated alkyl chlorides, especially tertiary alkyl chlorides, in transition-metal-catalyzed C-C bond formation remains challenging. Herein, we describe the development of a Ti

Indexed as

AlkanesAlkylationCatalysisFree RadicalsHydrocarbons, ChlorinatedMolecular StructureTitaniumAlkanesFree RadicalsHydrocarbons, ChlorinatedTitanium

Identifiers

PMID30303379
PMCPMC6530901

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.