ArticleJournal of biophotonics2019
Super-achromatic optical coherence tomography capsule for ultrahigh-resolution imaging of esophagus.
Article in Journal of biophotonics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Wireless, Deep-Seeing Smart Pill: A NIR-II Fluorescence Imaging Capsule Endoscope for Gastrointestinal Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Effectiveness of digital dispersion compensation in OCT.Biomedical optics express · 2025Article
- All-reflective tethered capsule endoscope for multimodal optical coherence tomography in the esophagus.Journal of biomedical optics · 2024Article
- Multifunctional Ablative Gastrointestinal Imaging Capsule (MAGIC) for Esophagus Surveillance and Interventions.BME frontiers · 2024Article
- Motionless volumetric structured light sheet microscopy.Biomedical optics express · 2023Article
- Towards OCT-Guided Endoscopic Laser Surgery-A Review.Diagnostics (Basel, Switzerland) · 2023Review
- Label-Free Metabolic Imaging In Vivo by Two-Photon Fluorescence Lifetime Endomicroscopy.ACS photonics · 2022Article
- Visualization and Validation of The Microstructures in The Airway Wall in vivo Using Diffractive Optical Coherence Tomography.Academic radiology · 2022Article
- Direct Visualization and Quantitative Imaging of Small Airway Anatomy In Vivo Using Deep Learning Assisted Diffractive OCT.IEEE transactions on bio-medical engineering · 2022Article
- Comparative Study of Conventional and Ultrahigh-resolution Optical Coherence Tomography Imaging in Esophageal Neoplasia.Techniques and innovations in gastrointestinal endoscopy · 2022Article
- Millimeter-scale chip-based supercontinuum generation for optical coherence tomography.Science advances · 2021Article
- A review of low-cost and portable optical coherence tomography.Progress in biomedical engineering (Bristol, England) · 2021Article
- Dual-modality optical coherence tomography and fluorescence tethered capsule endomicroscopy.Biomedical optics express · 2021Article
- Diagnosing colorectal abnormalities using scattering coefficient maps acquired from optical coherence tomography.Journal of biophotonics · 2021Article
- Stick-slip nonuniform rotation distortion correction in distal scanning optical coherence tomography catheters.Journal of innovative optical health sciences · 2020Article
- USB capsule endoscope for retrograde imaging of the esophagus.Journal of biomedical optics · 2020Article
- Low-cost, ultracompact handheld optical coherence tomography probe for in vivo oral maxillofacial tissue imaging.Journal of biomedical optics · 2020Article
- Robust, accurate depth-resolved attenuation characterization in optical coherence tomography.Biomedical optics express · 2020Article
- Optical coherence tomography-guided laser marking with tethered capsule endomicroscopy in unsedated patients.Biomedical optics express · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Endoscopic optical coherence tomography (OCT) is a noninvasive technology allowing for imaging of tissue microanatomies of luminal organs in real time. Conventional endoscopic OCT operates at 1300 nm wavelength region with a suboptimal axial resolution limited to 8-20 μm. In this paper, we present the first ultrahigh-resolution tethered OCT capsule operating at 800 nm and offering about 3- to 4-fold improvement of axial resolution (plus enhanced imaging contrast). The capsule uses diffractive optics to manage chromatic aberration over a full ~200 nm spectral bandwidth centering around 830 nm, enabling to achieve super-achromaticity and an axial resolution of ~2.6 μm in air. The performance of the OCT capsule is demonstrated by volumetric imaging of swine esophagus ex vivo and sheep esophagus in vivo, where fine anatomic structures including the sub-epithelial layers are clearly identified. The ultrahigh resolution and excellent imaging contrast at 800 nm of the tethered capsule suggest the potential of the technology as an enabling tool for surveillance of early esophageal diseases on awake patients without the need for sedation.
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Registered trials
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