Evidence map›Paper›PMID 30302554›Full record

ArticleCurrent microbiology2019

Adhesion-Related Immunomodulatory Activity of the Screened Lactobacillus plantarum from Sichuan Pickle.

Shanshan Chen, Pei Cao, Fengxuan Lang, Zhen Wu, Daodong Pan, Xiaoqun Zeng, Liwei Lian

Abstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Probiotic Potential ofFrontiers in microbiology · 2021
    Article
  3. Effect ofNutrients · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Shanshan ChenKey Laboratory of Animal Protein Deep Processing Technology of Zhejiang, School of Food and Pharmaceutical Science, Ningbo University, Ningbo, 315211, Zhejiang, People's Republic of China.
Pei CaoKey Laboratory of Animal Protein Deep Processing Technology of Zhejiang, School of Food and Pharmaceutical Science, Ningbo University, Ningbo, 315211, Zhejiang, People's Republic of China.
Fengxuan LangKey Laboratory of Animal Protein Deep Processing Technology of Zhejiang, School of Food and Pharmaceutical Science, Ningbo University, Ningbo, 315211, Zhejiang, People's Republic of China.
Zhen WuKey Laboratory of Animal Protein Deep Processing Technology of Zhejiang, School of Food and Pharmaceutical Science, Ningbo University, Ningbo, 315211, Zhejiang, People's Republic of China. woodsen@163.com.
Daodong PanKey Laboratory of Animal Protein Deep Processing Technology of Zhejiang, School of Food and Pharmaceutical Science, Ningbo University, Ningbo, 315211, Zhejiang, People's Republic of China. daodongpan@163.com.
Xiaoqun ZengKey Laboratory of Animal Protein Deep Processing Technology of Zhejiang, School of Food and Pharmaceutical Science, Ningbo University, Ningbo, 315211, Zhejiang, People's Republic of China.
Liwei LianNingbo Dairy Group, Ningbo, 315211, Zhejiang, People's Republic of China.
Ningbo University · CNNanjing Normal University · CNUniversity of Nottingham Ningbo China · CN

Funding

National Natural Science Foundation of China 31471598National Natural Science Foundation of China 31601487National Natural Science Foundation of China 31671869Natural Science Foundation of Zhejiang Province (CN) LY19C200005Ningbo Municipal Bureau of Science and Technology 2016C10022Open Funding of the Key Laboratory of Animal Protein Deep Processing Technology of Zhejiang ZX2015000928
6 · The paper itself

Abstract

Lactic acid bacteria are the majority fermentation starter in the traditional fermented foods. In this research, a promising Lactobacillus plantarum was isolated from Sichuan pickle and its adhesion properties were analyzed in simulated gastrointestinal fluid with different methods. Meanwhile, the immunomodulatory effect of this strain was also evaluated in the Caco-2 cells. Results found that adhesion-related mub genes and other genes like lsp and tuf were upregulated in different culture times. Furthermore, L. plantarum cultured at alkaline environment revealed some anti-inflammation activity through inhibited expression of cytokine IL-8 and increased expression of anti-inflammatory cytokine IL-10 in Caco-2 cells. The texture of yogurt after fermented by this kind of isolated strain was also investigated, which provides the foundation for the further development and application of this kind of strain in food production. More investigations need to be carried out to determine whether this probiotic contributes to regulation of intestinal flora and prevention of gut inflammation.

Indexed as

Bacterial AdhesionCaco-2 CellsCell Line, TumorCucumis sativusFermentationFermented FoodsHumansInterleukin-10Interleukin-8Lactiplantibacillus plantarumMicroscopy, Electron, ScanningProbioticsYogurtCXCL8 protein, humanIL10 protein, humanInterleukin-10Interleukin-8

Identifiers

PMID30302554
OpenAlexW2897676468

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.