ArticleBrain structure & function2019
Linking structural and effective brain connectivity: structurally informed Parametric Empirical Bayes (si-PEB).
Article in Brain structure & function, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Relating Cognition to both Brain Structure and Function: A Systematic Review of Methods.Brain connectivity · 2023Pooled it
- Effective connectivity between homologous cortices mediated by the corpus callosum: An axono-cortical evoked potentials study.Clinical neurophysiology practice · 2026Article
- Habit learning is associated with efficiently controlled network dynamics in naive macaque monkeys.Npj complexity · 2026Article
- Structurally informed resting-state effective connectivity recapitulates cortical hierarchy.bioRxiv : the preprint server for biology · 2025Article
- Habenula contributions to negative self-cognitions.Nature communications · 2025Article
- Interictal discharges spread along local recurrent networks between tubers and surrounding cortex.The Journal of physiology · 2025Article
- Structurally informed models of directed brain connectivity.Nature reviews. Neuroscience · 2025Review
- Macroscale coupling between structural and effective connectivity in the mouse brain.Scientific reports · 2024Article
- An information-theoretic framework for conditional causality analysis of brain networks.Network neuroscience (Cambridge, Mass.) · 2024Article
- A new causal centrality measure reveals the prominent role of subcortical structures in the causal architecture of the extended default mode network.Brain structure & function · 2023Article
- Brain effective connectome based on fMRI and DTI data: Bayesian causal learning and assessment.PloS one · 2023Article
- Case report: "Proust phenomenon" after right posterior cerebral artery occlusion.Frontiers in neurology · 2023Article
- Structure supports function: Informing directed and dynamic functional connectivity with anatomical priors.Network neuroscience (Cambridge, Mass.) · 2022Article
- A serotonergic biobehavioral signature differentiates cocaine use disorder participants administered mirtazapine.Translational psychiatry · 2022Article
- Influence of periaqueductal gray on other salience network nodes predicts social sensitivity.Human brain mapping · 2022Article
- The functional characterization of callosal connections.Progress in neurobiology · 2022Review
- Simultaneous Normalization and Compensatory Changes in Right Hemisphere Connectivity during Aphasia Therapy.Brain sciences · 2021Article
- Closed-loop neuromodulation in an individual with treatment-resistant depression.Nature medicine · 2021Article
- fMRI-Based Effective Connectivity in Surgical Remediable Epilepsies: A Pilot Study.Brain topography · 2021Article
- Ageing and the Ipsilateral M1 BOLD Response: A Connectivity Study.Brain sciences · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Despite the potential for better understanding functional neuroanatomy, the complex relationship between neuroimaging measures of brain structure and function has confounded integrative, multimodal analyses of brain connectivity. This is particularly true for task-related effective connectivity, which describes the causal influences between neuronal populations. Here, we assess whether measures of structural connectivity may usefully inform estimates of effective connectivity in larger scale brain networks. To this end, we introduce an integrative approach, capitalising on two recent statistical advances: Parametric Empirical Bayes, which provides group-level estimates of effective connectivity, and Bayesian model reduction, which enables rapid comparison of competing models. Crucially, we show that structural priors derived from high angular resolution diffusion imaging on a dynamic causal model of a 12-region network-based on functional MRI data from the same subjects-substantially improve model evidence (posterior probability 1.00). This provides definitive evidence that structural and effective connectivity depend upon each other in mediating distributed, large-scale interactions in the brain. Furthermore, this work offers novel perspectives for understanding normal brain architecture and its disintegration in clinical conditions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.