Evidence map›Paper›PMID 30302419›Full record

ArticleAmerican journal of ophthalmology case reports2018

Trigeminal hypertrophic interstitial neuropathy presenting as unilateral proptosis, ptosis, tearing, and facial neuralgia.

Elizabeth R Duvall, Jennifer Pan, Kim Tien T Dinh, Majd Al Shaarani, Golden Pan, Marlyn P Langford, William A Byrd

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of ophthalmology case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Elizabeth R DuvallDepartment of Ophthalmology, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
Jennifer PanDepartment of Ophthalmology, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
Kim Tien T DinhDepartment of Ophthalmology, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
Majd Al ShaaraniDepartment of Pathology, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
Golden PanMedical Imaging Diagnostic Associates, Laredo Medical Center, Laredo, TX, 78045, USA.
Marlyn P LangfordDepartment of Ophthalmology, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
William A ByrdDepartment of Ophthalmology, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
Louisiana State University Health Sciences Center Shreveport · USLaredo Community College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo show the utility of MRI and histology in diagnosing rare cases of trigeminal hypertrophic interstitial neuropathy (HIN). OBSERVATIONS: A 57-year-old African-American woman presented with a 4-year history of right eye proptosis with tearing, headaches, and worsening right-sided trigeminal neuralgia symptoms and jaw pain. HIV and diabetes tests were negative and thyroid function was normal. MRI identified abnormal thickening of all trigeminal nerve divisions and proptosis secondary to right trigeminal nerve V1 division enlargement. The excised tissue contained S-100 positive Schwann cells in an onion-bulb pattern. Headaches resolved, but proptosis and mild trigeminal neuralgia remained 1 year post-surgery. CONCLUSIONS AND IMPORTANCE: Trigeminal HIN is very rare, but presents as chronic progressive ocular symptoms with trigeminal neuralgia. Trigeminal nerve hypertrophy is identified by MRI and confirmed histopathologically by detection of Schwann cells in an onion bulb formation.

Indexed as

Cranial nerveExophthalmosOnion bulbSchwann cellTrigeminal nerve

Identifiers

PMID30302419
PMCPMC6174841
OpenAlexW2895357167

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.