Evidence map›Paper›PMID 30302236›Full record

ArticleInternational journal of hematologic oncology2018

Chart review across EU5 in MM post-ASCT patients.

John Ashcroft, Davneet Judge, Sujith Dhanasiri, Gavin Taylor-Stokes, Chloe Middleton

Abstract read
In one paragraph

Article in International journal of hematologic oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Cost-Effectiveness of Post-Autotransplant Lenalidomide in Persons with Multiple Myeloma.Mediterranean journal of hematology and infectious diseases · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

John AshcroftDepartment of Haematology, Mid-Yorkshire NHS Trust, Wakefield, WF1 4DG2, UK.
Davneet JudgeAdelphi Real World, Bollington, Cheshire, SK10 5JB, UK.
Sujith DhanasiriCelgene International, Boudry, CH-2017, Switzerland.
Gavin Taylor-StokesAdelphi Real World, Bollington, Cheshire, SK10 5JB, UK.
Chloe MiddletonAdelphi Real World, Bollington, Cheshire, SK10 5JB, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo understand the current treatment patterns, clinical outcomes and healthcare resource utilization-associated costs for multiple myeloma patients, post autologous stem cell transplant (ASCT) across Europe. PATIENTS &

methodsMedical records were used to abstract data for 337 multiple myeloma patients who had received ASCT.

resultsFollowing ASCT, 7% received maintenance therapy prior to progression. Lenalidomide was the most frequently prescribed maintenance, second- and third-line therapy. Monthly resource use was considerably lower in patients who received maintenance therapy (€638.14 vs €1001.74). Median time to progression was longer for patients who had received maintenance therapy.

conclusionThe study highlights the diversity in current treatment patterns post-ASCT. Results suggest patients who receive maintenance therapy have a prolonged remission period, and as a result their associated healthcare resource utilization is spread across the treatment pathway.

Indexed as

healthcare resource utilizationlenalidomidemaintenance treatmentmultiple myelomareal worldstem cell transplantationtreatment patterns

Identifiers

PMID30302236
PMCPMC6176952

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.