Evidence map›Paper›PMID 30302205›Full record

ArticleInternational journal of hematologic oncology2016

Five-year direct costs of acute lymphoblastic leukemia pediatric patients undergoing allogeneic stem cell transplant.

Richard T Maziarz, Annie Guérin, Geneviève Gauthier, Julie Heroux, Maryia Zhdanava, Eric Q Wu, Simu K Thomas, Lei Chen

Abstract read
In one paragraph

Article in International journal of hematologic oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Richard T MaziarzDivision of Hematology & Medical Oncology, Knight Cancer Institute, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239-3098, USA.
Annie GuérinAnalysis Group Inc., 1000 De La Gauchetière Ouest, Bureau 1200, Montréal, QC H3B 4W5, Canada.
Geneviève GauthierAnalysis Group Inc., 1000 De La Gauchetière Ouest, Bureau 1200, Montréal, QC H3B 4W5, Canada.
Julie HerouxAnalysis Group Inc., 1000 De La Gauchetière Ouest, Bureau 1200, Montréal, QC H3B 4W5, Canada.
Maryia ZhdanavaAnalysis Group Inc., 1000 De La Gauchetière Ouest, Bureau 1200, Montréal, QC H3B 4W5, Canada.
Eric Q WuAnalysis Group Inc., 14th floor, 111 Huntington Ave, Boston, MA 02199-7668, USA.
Simu K ThomasNovartis Pharmaceuticals Corporation, East Hanover, NJ 07936-1080, USA.
Lei ChenNovartis Pharmaceuticals Corporation, East Hanover, NJ 07936-1080, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess the 5-year healthcare resource utilization (HRU) and direct payer costs following allogeneic hematopoietic stem cell transplants (HSCTs) in acute lymphoblastic leukemia pediatric patients using data from two large US administrative databases. PATIENTS &

methodsAmong the 209 patients with acute lymphoblastic leukemia, HRU and costs were described over the up to 5 years after the HSCT.

resultsHRU and costs following the HSCTs were substantial. The highest average costs and most intensive HRU were observed within the first year following the HSCTs (49 outpatient visits; 29 laboratory service visits; 68 inpatient days), with a first year cost of US$683,099 and substantial costs over the following years.

conclusionHRU and direct costs associated with allogeneic HSCTs are substantial.

Indexed as

acute lymphoblastic leukemiaallogeneic stem cell transplantationdirect costseconomic burdenhealthcare resource utilizationpediatric patients

Identifiers

PMID30302205
PMCPMC6171974

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.