Evidence map›Paper›PMID 30302170›Full record

ArticlePrzeglad gastroenterologiczny2018

Safety analysis of endoscopic haemostasis using a high-frequency live tissue electric welding device - EKVZ300 PATONMED.

Yegor Tryliskyy, Andrii Kebkalo, Chee S Wong, Sergii Rublenko, Mykhailo Rublenko, Mykola Ilnytskiy, Ievgenii Negria, Vladislav Hordovskiy

Open access · goldAbstract read
In one paragraph

Article in Przeglad gastroenterologiczny, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
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  4. AnFrontiers in bioengineering and biotechnology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Yegor TryliskyyDepartment of Surgery and Proctology, Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine.
Andrii KebkaloDepartment of Surgery and Proctology, Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine.
Chee S WongDepartment of Clinical Surgery, The University of Edinburgh, Edinburgh, UK.
Sergii RublenkoDepartment of Veterinary Medicine, Bila Tserkva National Agrarian University, Bila Tserkva, Ukraine.
Mykhailo RublenkoDepartment of Veterinary Medicine, Bila Tserkva National Agrarian University, Bila Tserkva, Ukraine.
Mykola IlnytskiyDepartment of Veterinary Medicine, Bila Tserkva National Agrarian University, Bila Tserkva, Ukraine.
Ievgenii NegriaDepartment of Endoscopy, Kiev City Clinical Hospital No. 8, Kyiv, Ukraine.
Vladislav HordovskiyDepartment of Surgery and Proctology, Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine.
Bila Tserkva National Agrarian University · UAShupyk National Healthcare University of Ukraine · UAUniversity of Edinburgh · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe method of a bipolar high-frequency welding (HFEW) of soft living tissues of animals and humans has been used in various areas of surgery. However, it has not been utilized in endoscopic gastrointestinal procedures yet. HFEW has strong potential to be used in gastrointestinal endoscopic procedures due to the competitive cost of generator devices and due to its proven ability to coagulate vessels of wide diameter as compared to standard electrocautery devices.

aimTo investigate the effectiveness of the endoscopic haemostasis using HFEW generator device - 300 PATONMED - in a porcine model of arterial gastrointestinal bleeding. MATERIAL AND

methodsA porcine model of arterial gastrointestinal bleeding was created. A 300 PATONMED set to the "welding" regime and a flexible 7 Fr bipolar coagulation probe with two electrodes on the tip fashioned spirally attached to convey energy were tested. Once bleeding from the artery had been initiated, the bipolar probe was applied to coagulate the bleeding site. Animals were observed for clinical evidence of recurrent bleeding and subsequently were euthanised for histological examination.

resultsA total of 10 experiments were successfully completed. An optimal haemostatic effect was achieved with durations of cautery of five to eight seconds in all animals. Continuous observation after haemostasis revealed no evidence of re-bleeding. No systemic side-effects of the technique were observed. Histological examination has shown that the peripheral thermal injury area that surrounded the coagulation zone did not spread beyond the mucosal layer in depth and 2 mm in width.

conclusionsThis animal study provided evidence for the safety of an HFEW in the treatment of gastrointestinal bleeding. The advantages of this technology are smokeless operative area, no tissue overheating, minimal necrosis and damage to surrounding gastric tissue, and the fact that the area of HFEW is confined to the area of the electrodes.

Indexed as

endoscopic haemostasissafety analysis

Identifiers

PMID30302170
PMCPMC6173082
OpenAlexW2895132609

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.