ArticleWorld journal of emergency surgery : WJES2018
Risk factors for mortality in the late amputation of necrotizing fasciitis: a retrospective study.
Article in World journal of emergency surgery : WJES, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 51 citations in OpenAlex.
- Necrotizing Fasciitis of the Extremities: Microbial Spectrum, Antimicrobial Resistance, and Clinical Outcomes in a 7-Year Retrospective Cohort Study.Medicina (Kaunas, Lithuania) · 2026Article
- Clinical Severity and Systemic Inflammatory Indices as Predictors of In-Hospital Mortality After Limb Amputation a Retrospective Cohort Study.Journal of clinical medicine · 2025Article
- Characteristics, treatments, and outcomes of patients with necrotizing soft tissue infections: a Dutch multicenter cohort study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Article
- Predictors of clinical outcomes in necrotizing fasciitis: a ten year study.International orthopaedics · 2025Article
- Epidemiology and prognostic factors of necrotizing fasciitis in resource-limited regions based on 119 cases.Scientific reports · 2025Article
- Article
- Consensus on the Diagnosis and Treatment of Adult Necrotizing Fasciitis (2025 Edition).Burns & trauma · 2025Article
- Socioeconomic status affects amputation and mortality rates in necrotizing fasciitis patients.International orthopaedics · 2024Article
- Can The Systemic Immune-Inflammation Index (SII) and Charlson Comorbidity Index (CCI) be used to predict mortality in patients with necrotizing fasciitis?International orthopaedics · 2024Article
- Association between time to surgery and hospital mortality in patients with community-acquired limb necrotizing fasciitis: an 11-year multicenter retrospective cohort analysis.BMC infectious diseases · 2024Article
- Machine Learning Approach to ClassifyInfection and drug resistance · 2024Article
- Initial skin necrosis presentation at emergency room was associated with fulminant clinical course and mortality in patients with Vibrio necrotizing fasciitis.Scientific reports · 2023Article
- Risk Factors for Predicting Mortality and Amputation of Patients with Necrotizing Soft-Tissue Infections: Retrospective Analysis of 111 Cases from a Single Medical Center.Emergency medicine international · 2023Article
- In-hospital mortality associated with necrotizing soft tissue infection due to Vibrio vulnificus: a matched-pair cohort study.World journal of emergency surgery : WJES · 2022Article
- Distribution and drug sensitivity of pathogenic bacteria in diabetic foot ulcer patients with necrotizing fasciitis at a diabetic foot center in China.BMC infectious diseases · 2022Article
- [Two cases ofZhonghua shao shang yu chuang mian xiu fu za zhi · 2022Article
- Necrotizing Soft Tissue Infections in Intensive Care.Journal of intensive care medicine · 2022Observational
- Necrotizing fasciitis, causative agents and management: a five-year retrospective study in two tertiary care hospitals in Central Malaysia.International orthopaedics · 2021Article
- Utility of the Lactate/Albumin Ratio as a Predictor for Mortality in Necrotizing Fasciitis Patients.Emergency medicine international · 2021Article
- Novel Clinical Risk Scoring Model for Predicting Amputation in Patients With Necrotizing Fasciitis: The ANF Risk Scoring System.Frontiers in medicine · 2021Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Necrotizing fasciitis (NF) is a rapidly progressive infectious disease that primarily involves the fascia and subcutaneous tissue. If not promptly treated, it can lead to morbidity as well as mortality. It can affect any part of the body, most commonly the extremities. Early and aggressive surgical treatment is the proper way of management. The purpose of this study was to identify the risk factors for mortality in late amputation among NF patients that may be used in routine clinical practice to prevent mortality. Methods: A retrospective cohort study of hospitalized patients with NF was conducted in a tertiary teaching hospital in Taiwan between March 2015 and March 2018. All collected data were statistically analyzed. Results: A total of 582 patients with NF were included; 35 of them had undergone amputation (7 primary and 28 late amputations), with a 6% amputation rate. Thirteen amputated patients still died eventually (all in the late amputation group). Significant risk factors for mortality identified in the late amputation group included hemorrhagic bullae ( Conclusion: NF patients with hemorrhagic bullae, comorbidity with peripheral vascular disease, presence of bacteremia, or LRINEC score > 8 should receive early and primary amputation in order to prevent mortality.
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