Evidence map›Paper›PMID 30302114›Full record

ArticleDrugs in context2018

Eosinophilic fasciitis: a case series with an emphasis on therapy and induction of remission.

Rechelle Tull, William D Hoover, Jacqueline F De Luca, William W Huang, Joseph L Jorizzo

Open access · goldAbstract read
In one paragraph

Article in Drugs in context, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. [Eosinophilic fascitis: A case report and literature review].Revista medica del Instituto Mexicano del Seguro Social · 2026
    Review
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  9. Eosinophilic Fasciitis - Report of Three Cases and Review of the Literature.Open access Macedonian journal of medical sciences · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rechelle TullDepartment of Dermatology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
William D HooverDepartment of Dermatology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Jacqueline F De LucaDepartment of Dermatology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
William W HuangDepartment of Dermatology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Joseph L JorizzoDepartment of Dermatology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Wake Forest University · USUniversity of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eosinophilic fasciitis is an uncommon connective tissue disorder that affects patients of all ages, resulting in significant morbidity. Systemic corticosteroids can induce remission of disease. However, there is no universally accepted treatment ladder for eosinophilic fasciitis. This case series evaluates treatment efficacy in patients with eosinophilic fasciitis seen at Wake Forest University Department of Dermatology outpatient clinics. Patient charts were screened using ICD-9 diagnosis code 710.9 (unspecified diffuse connective tissue disease) to identify patients with eosinophilic fasciitis (n=10) seen at our institution. Patients were treated for an average 24 months with a combination of methotrexate and prednisone therapy, unless one or both were contraindicated, with each medication tapered conservatively to prevent disease flares. Alternate treatments included mycophenolate mofetil with prednisone, azathioprine with prednisone, prednisone monotherapy, and methotrexate monotherapy. Disease remission off therapy and on low-dose therapy was 66 and 70%, respectively. Our first-line therapy of concomitant methotrexate and prednisone is well-tolerated and effective for managing patients with eosinophilic fasciitis. Our study was limited to cases seen at a single academic institution.

Indexed as

connective tissue diseasescorticosteroidsdermatologydrug therapyeosinophilic fasciitisimmunosuppressive agentsmethotrexateprednisone

Identifiers

PMID30302114
PMCPMC6172017
OpenAlexW2895213813

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.