Evidence map›Paper›PMID 30302051›Full record

ArticleJournal of clinical and experimental hepatology2018

Primary Hepatic Leiomyosarcoma: Histopathologist's Perspective of a Rare Case.

Suvradeep Mitra, Sahaj Rathi, Uma Debi, Radha K Dhiman, Ashim Das

Abstract read
In one paragraph

Article in Journal of clinical and experimental hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Suvradeep MitraSenior Resident, Department of Histopathology, PGIMER, Chandigarh, India.
Sahaj RathiSenior Resident, Department of Hepatology, PGIMER, Chandigarh, India.
Uma DebiAssistant Professor, Department of Radiology, PGIMER, Chandigarh, India.
Radha K DhimanProfessor and Head, Department of Hepatology, PGIMER, Chandigarh, India.
Ashim DasProfessor, Department of Histopathology, PGIMER, Chandigarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary hepatic leiomyosarcoma is a rare primary mesenchymal tumor of the liver requiring exclusion of any other primary site of origin and histological and immunohistochemical exclusion of other hepatic/extrahepatic tumors with spindle cell morphology. Only about 70 cases are reported in the English literature and many of these tumors have predisposing conditions in the form of immunosuppression or associated malignancies. The occurrence of this tumor in the immunocompetent individual is also known. Histomorphology of this tumor shows a spindle cell lesion which needs to be distinguished from other spindle cell lesions of this region. The main diagnostic challenge of this tumor lies in its rarity, lack of awareness and morphological mimickers in the given site. A complete range of immunohistochemical markers is required to distinguish the lesion from its close morphological mimickers. Here, we discuss a case of primary hepatic leiomyosarcoma in an adult female patient with detailed histomorphological differentials and respective immunoprofiles.

Indexed as

AFP, Alpha FetoproteinCEA, Carcinoembryonic AntigenCEMRI, Contrast Enhanced Magnetic Resonance ImagingEBER-ISHEBER-ISH, Epstein Barr Encoded RNA-In Situ HybridizationEBV, Epstein-Barr VirusFDG, FluorodeoxyglucoseFNAC, Fine Needle Aspiration Cytologygastrointestinal stromal tumorGIST, Gastrointestinal Stromal TumorimmunocompetentPET-CT, Positron Emission Tomography – Computed Tomographyprimary hepatic leiomyosarcomaSMASMA, Smooth Muscle AntigenTPCT, Triple Phasic Computed TomographyUGIE, Upper Gastrointestinal EndoscopyUSG, Ultrasonography

Identifiers

PMID30302051
PMCPMC6175749

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.