Evidence map›Paper›PMID 30302024›Full record

ArticleScientific reports2018

Superiority of SpiroZin2 Versus FluoZin-3 for monitoring vesicular Zn

Yu Han, Jacob M Goldberg, Stephen J Lippard, Amy E Palmer

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Tools and techniques for illuminating the cell biology of zinc.Biochimica et biophysica acta. Molecular cell research · 2021
    Review
  15. ZIGIR, a Granule-Specific ZnCell reports · 2020
    Article
  16. Remodeling of ZnMetallomics : integrated biometal science · 2020
    Article
  17. Intracellular ZnScientific reports · 2019
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yu HanDepartment of Biochemistry and BioFrontiers Institute, University of Colorado, Boulder, CO, 80303, USA.
Jacob M GoldbergDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139-4307, USA.ORCID http://orcid.org/0000-0002-8004-3769
Stephen J LippardDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139-4307, USA.
Amy E PalmerDepartment of Biochemistry and BioFrontiers Institute, University of Colorado, Boulder, CO, 80303, USA. amy.palmer@colorado.edu.ORCID http://orcid.org/0000-0002-5794-5983
Massachusetts Institute of Technology · USUniversity of Colorado Boulder · US

Funding

Investigation of Zinc Neurochemistry by Optical Sensing and MRIR01GM065519 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI NOLAN, ELIZABETH M · 2002 to 2017
$5.3M
Regulation of Cell Signaling by Transition Metal DynamicsDP1GM114863 · NIGMS · UNIVERSITY OF COLORADO · PI PALMER, AMY E · 2014 to 2018
$3.8M
Technologies to Define and Map Novel Interorganelle Macromolecular InteractionsR01GM105997 · NIGMS · UNIVERSITY OF COLORADO · PI AHN, NATALIE G., PALMER, AMY E · 2013 to 2016
$1.6M
Multicolor Fluorescent Sensors for Imaging Zinc Dynamics in CellsF32GM109516 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GOLDBERG, JACOB M. · 2014 to 2016
$164k
NIGMS NIH HHS DP1 GM114863NIGMS NIH HHS F32 GM109516NIGMS NIH HHS R01 GM065519NIGMS NIH HHS R01 GM105997
6 · The paper itself

Abstract

Small-molecule fluorescent probes are powerful and ubiquitous tools for measuring the concentration and distribution of analytes in living cells. However, accurate characterization of these analytes requires rigorous evaluation of cell-to-cell heterogeneity in fluorescence intensities and intracellular distribution of probes. In this study, we perform a parallel and systematic comparison of two small-molecule fluorescent vesicular Zn

Indexed as

AnimalsEpithelial CellsFemaleFluorescent DyesHomeostasisLactationLysosomesMammary Glands, AnimalMicePolycyclic CompoundsZincFluorescent DyesFluoZin-3Polycyclic CompoundsZinc

Identifiers

PMID30302024
PMCPMC6177427
OpenAlexW2895349004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.