ArticleNature communications2018
A mechanoelectrical mechanism for detection of sound envelopes in the hearing organ.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 35 citations in OpenAlex.
- 40-Hz auditory stimulation for intracranial interictal activity: A pilot study.Acta neurologica Scandinavica · 2021Trial
- Article
- A maturational frequency discrimination deficit may explain developmental language disorder.Psychological review · 2024Article
- Signal processing and stimulation potential within the ascending auditory pathway: a review.Frontiers in neuroscience · 2023Review
- The reticular lamina and basilar membrane vibrations in the transverse direction in the basal turn of the living gerbil cochlea.Scientific reports · 2022Article
- Cubic and quadratic distortion products in vibrations of the mouse cochlear apex.JASA express letters · 2022Article
- An outer hair cell-powered global hydromechanical mechanism for cochlear amplification.Hearing research · 2022Article
- Outer hair cell driven reticular lamina mechanical distortion in living cochleae.Hearing research · 2022Review
- The Influence of Male- and Female-Spoken Vowel Acoustics on Envelope-Following Responses.Seminars in hearing · 2022Review
- A flexible anatomical set of mechanical models for the organ of Corti.Royal Society open science · 2021Article
- The origin of mechanical harmonic distortion within the organ of Corti in living gerbil cochleae.Communications biology · 2021Article
- Nonlinearity of intracochlear motion and local cochlear microphonic: Comparison between guinea pig and gerbil.Hearing research · 2021Article
- Postnatal structural development of mammalian Basilar Membrane provides anatomical basis for the maturation of tonotopic maps and frequency tuning.Scientific reports · 2021Article
- Direct Delivery of Antisense Oligonucleotides to the Middle and Inner Ear Improves Hearing and Balance in Usher Mice.Molecular therapy : the journal of the American Society of Gene Therapy · 2020Article
- Characterisation of the static offset in the travelling wave in the cochlear basal turn.Pflugers Archiv : European journal of physiology · 2020Article
- Revealing the morphology and function of the cochlea and middle ear with optical coherence tomography.Quantitative imaging in medicine and surgery · 2019Review
- Drug Diffusion Along an Intact Mammalian Cochlea.Frontiers in cellular neuroscience · 2019Article
Corrections and comments
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Authors and funding
13 authors at 7 institutions in 5 countries.
Funding
Abstract
To understand speech, the slowly varying outline, or envelope, of the acoustic stimulus is used to distinguish words. A small amount of information about the envelope is sufficient for speech recognition, but the mechanism used by the auditory system to extract the envelope is not known. Several different theories have been proposed, including envelope detection by auditory nerve dendrites as well as various mechanisms involving the sensory hair cells. We used recordings from human and animal inner ears to show that the dominant mechanism for envelope detection is distortion introduced by mechanoelectrical transduction channels. This electrical distortion, which is not apparent in the sound-evoked vibrations of the basilar membrane, tracks the envelope, excites the auditory nerve, and transmits information about the shape of the envelope to the brain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.