Evidence map›Paper›PMID 30301969›Full record

ArticleScientific reports2018

Uncovering association networks through an eQTL analysis involving human miRNAs and lincRNAs.

Paulo R Branco, Gilderlanio S de Araújo, Júnior Barrera, Guilherme Suarez-Kurtz, Sandro José de Souza

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. A hybrid model for predicting response to risperidone after first-episode psychosis.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Paulo R BrancoBioinformatics Multidisciplinary Environment (BioME), Instituto Metrópole Digital, UFRN, Natal, Brazil.
Gilderlanio S de AraújoBioinformatics Multidisciplinary Environment (BioME), Instituto Metrópole Digital, UFRN, Natal, Brazil.
Júnior BarreraInstituto de Matemática e Estatística, Universidade de São Paulo, São Paulo, Brazil.
Guilherme Suarez-KurtzInstituto Nacional do Câncer, Rio de Janeiro, Brazil.
Sandro José de SouzaBioinformatics Multidisciplinary Environment (BioME), Instituto Metrópole Digital, UFRN, Natal, Brazil. sandro@neuro.ufrn.br.
Universidade Federal do Rio Grande do Norte · BRInstituto Nacional do Câncer · BRPorto Digital (Brazil) · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-coding RNAs (ncRNA) have an essential role in the complex landscape of human genetic regulatory networks. One area that is poorly explored is the effect of genetic variations on the interaction between ncRNA and their targets. By integrating a significant amount of public data, the present study cataloged the vast landscape of the regulatory effect of microRNAs (miRNA) and long intergenic noncoding RNAs (lincRNA) in the human genome. An expression quantitative trait loci (eQTL) analysis was used to identify genetic variants associated with miRNA and lincRNA and whose genotypes affect gene expression. Association networks were built for eQTL associated to traits of clinical and/or pharmacological relevance.

Indexed as

Gene Expression RegulationGene Regulatory NetworksGenetic Association StudiesGenome, HumanGenotypeHumansMicroRNAsPolymorphism, Single NucleotideQuantitative Trait LociRNA, Long NoncodingMicroRNAsRNA, Long Noncoding

Identifiers

PMID30301969
PMCPMC6177424
OpenAlexW2894571123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.