Evidence map›Paper›PMID 30301869›Full record

ArticleThe Journal of general physiology2018

Nebulin increases thin filament stiffness and force per cross-bridge in slow-twitch soleus muscle fibers.

Masataka Kawai, Tarek S Karam, Justin Kolb, Li Wang, Henk L Granzier

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of general physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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  7. Fast skeletal myosin-binding protein-C regulates fast skeletal muscle contraction.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  8. Article
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  12. Nebulin: big protein with big responsibilities.Journal of muscle research and cell motility · 2020
    Review
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Masataka KawaiDepartments of Anatomy and Cell Biology, and Internal Medicine, College of Medicine, University of Iowa, Iowa City, IA masataka-kawai@uiowa.edu.ORCID 0000-0002-3219-3527
Tarek S KaramDepartments of Anatomy and Cell Biology, and Internal Medicine, College of Medicine, University of Iowa, Iowa City, IA.
Justin KolbDepartment of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ.
Li WangDepartments of Anatomy and Cell Biology, and Internal Medicine, College of Medicine, University of Iowa, Iowa City, IA.
Henk L GranzierDepartment of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ.
University of Iowa · USUniversity of Arizona · US

Funding

Roles of Nebulin in Structure and Function of Striated MuscleR01AR053897 · NIAMS · UNIVERSITY OF ARIZONA · PI Henk L. GRANZIER · 2007 to 2026
$7.4M
NIAMS NIH HHS R01 AR053897
6 · The paper itself

Abstract

Nebulin (Neb) is associated with the thin filament in skeletal muscle cells, but its functions are not well understood. For this goal, we study skinned slow-twitch soleus muscle fibers from wild-type (Neb

Indexed as

Muscle TonusAdenosine TriphosphateAnimalsFemaleMiceMice, KnockoutMuscle Fibers, Slow-TwitchMuscle ProteinsMuscle, SkeletalTropomyosinAdenosine TriphosphateMuscle ProteinsnebulinTropomyosin

Identifiers

PMID30301869
PMCPMC6219688
OpenAlexW2896274837

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.