Evidence map›Paper›PMID 30301855›Full record

ArticlemBio2018

Inducible Nitric Oxide Synthase Is a Key Host Factor for

Hironori Bando, Youngae Lee, Naoya Sakaguchi, Ariel Pradipta, Ji Su Ma, Shun Tanaka, Yihong Cai, Jianfa Liu, Jilong Shen, Yoshifumi Nishikawa and 2 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Animals : an open access journal from MDPI · 2025
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  7. Review
  8. Review
  9. Article
  10. Frontiers in cellular and infection microbiology · 2024
    Article
  11. Review
  12. Aging · 2023
    Article
  13. Nitric oxide in parasitic infections: a friend or foe?Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022
    Review
  14. Review
  15. Article
  16. Cells · 2022
    Article
  17. The strategies of NLRP3 inflammasome to combatFrontiers in immunology · 2022
    Review
  18. Secreted Effectors Modulating Immune Responses toLife (Basel, Switzerland) · 2021
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Hironori BandoDepartment of Immunoparasitology, Research Institute for Microbial Diseases, Osaka, Japan.
Youngae LeeDepartment of Immunoparasitology, Research Institute for Microbial Diseases, Osaka, Japan.
Naoya SakaguchiDepartment of Immunoparasitology, Research Institute for Microbial Diseases, Osaka, Japan.
Ariel PradiptaDepartment of Immunoparasitology, Research Institute for Microbial Diseases, Osaka, Japan.
Ji Su MaDepartment of Immunoparasitology, Research Institute for Microbial Diseases, Osaka, Japan.
Shun TanakaDepartment of Immunoparasitology, Research Institute for Microbial Diseases, Osaka, Japan.
Yihong CaiLaboratory of Immunoparasitology, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan.
Jianfa LiuDepartment of Pathology and Pathogenic Biology, Medical College of Ningbo University, Ningbo City, China.
Jilong ShenInstitute of Zoonoses, The Key Laboratory of Pathogen Biology, The Key Laboratory of Zoonoses, Anhui Medical University, Hefei, Anhui, China.
Yoshifumi NishikawaNational Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.
Miwa SasaiDepartment of Immunoparasitology, Research Institute for Microbial Diseases, Osaka, Japan.
Masahiro YamamotoDepartment of Immunoparasitology, Research Institute for Microbial Diseases, Osaka, Japan myamamoto@biken.osaka-u.ac.jp.
Microbial Chemistry Research Foundation · JPOsaka University · JPAnhui Medical University · CNNingbo University · CNObihiro University of Agriculture and Veterinary Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although

Indexed as

AnimalsAntigens, ProtozoanCell LineCoculture TechniquesCRISPR-Cas SystemsHepatocytesHost-Parasite InteractionsHumansIndoleamine-Pyrrole 2,3,-DioxygenaseInterferon-gammaInterleukin-1betaMiceMice, Inbred C57BLMonocytesNitric Oxide Synthase Type IINLR Family, Pyrin Domain-Containing 3 ProteinAntigens, ProtozoanIDO1 protein, humanIFNG protein, humanIL1B protein, humanIndoleamine-Pyrrole 2,3,-DioxygenaseInterferon-gammaInterleukin-1betaNitric Oxide Synthase Type IINLR Family, Pyrin Domain-Containing 3 ProteinNLRP3 protein, humanNOS2 protein, humanProtozoan ProteinsVirulence Factorscell-autonomous immunityhost-parasite interactionhuman immunologyimmune suppressioninterferonToxoplasma gondii

Identifiers

PMID30301855
PMCPMC6178625
OpenAlexW2896375196

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.