ArticlemBio2018
Octopaminergic Signaling Mediates Neural Regulation of Innate Immunity in Caenorhabditis elegans.
Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 70 citations in OpenAlex.
- Virus specific impacts on honey bee flight performance are mediated by the octopamine pathway.bioRxiv : the preprint server for biology · 2026Article
- Neural regulation of infection resolution prevents ER stress and tissue damage.bioRxiv : the preprint server for biology · 2026Article
- NMDA Receptor Subunit NMR-2 Regulates Pathogen-Induced Immune Responses via the Nervous System inbioRxiv : the preprint server for biology · 2026Article
- Single-type neuron transcriptomics uncovers cell-type-specific regulators of host defense inbioRxiv : the preprint server for biology · 2026Article
- Neurotransmitter signaling in molecular and behavioral immune responses to pathogens inMicrobiology and molecular biology reviews : MMBR · 2025Review
- The GPCR NMUR-1 mediates neural regulation of energy homeostasis in response to pathogen infection.Infection and immunity · 2025Article
- Distinct responses to non-autonomous UPRCommunications biology · 2025Article
- TheiScience · 2025Article
- GPCR Sense Communication Among Interaction Nematodes with Other Organisms.International journal of molecular sciences · 2025Review
- Modulation by NPY/NPF-like receptor underlies experience-dependent, sexually dimorphic learning.Nature communications · 2025Article
- Modeling Host-Pathogen Interactions inInternational journal of molecular sciences · 2024Review
- Antagonism between neuropeptides and monoamines in a distributed circuit for pathogen avoidance.Cell reports · 2024Article
- ADARs regulate cuticle collagen expression and promote survival to pathogen infection.BMC biology · 2024Article
- Article
- Article
- Effect of aminergic signaling on the humoral innate immunity response ofFrontiers in physiology · 2023Article
- Pathogen infection induces specific transgenerational modifications to gene expression and fitness inFrontiers in physiology · 2023Article
- A pals-25 gain-of-function allele triggers systemic resistance against natural pathogens of C. elegans.PLoS genetics · 2022Article
- Article
- Reduced CaFrontiers in neuroscience · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Upon pathogen infection, the nervous system regulates innate immunity to confer coordinated protection to the host. However, the precise mechanisms of such regulation remain unclear. Previous studies have demonstrated that OCTR-1, a putative G protein-coupled receptor for catecholamine, functions in the sensory neurons designated "ASH" to suppress innate immune responses in
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.