ArticleBMC musculoskeletal disorders2018
Coating the plate with antibiotic cement to treat early infection after fracture fixation with retention of the implants: a technical note.
Article in BMC musculoskeletal disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Antibiotic cement coating in orthopedic surgery: a systematic review of reported clinical techniques.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2021Pooled it
- Osseous union after antibiotic cement application with retention of stable orthopaedic hardware in fracture-related infections without union.OTA international : the open access journal of orthopaedic trauma · 2025Article
- Review
- Arthroscopic debridement and antibiotic-loaded cement for treatment of chronic infected tibial tunnel post-ACL reconstruction: A case report.International journal of surgery case reports · 2024Article
- Early Management for Fracture-Related Infection: A Literature Review.Healthcare (Basel, Switzerland) · 2024Review
- Antibiotic-loaded hydroxyapatite scaffolds fabricated fromInternational journal of pharmaceutics: X · 2023Article
- Current Concepts of Fracture-Related Infection.International journal of clinical practice · 2023Review
- Antibiotic cement-coated plate is a viable and efficient technique for the definitive management of metaphyseal septic nonunions of the femur and tibia.Revista do Colegio Brasileiro de Cirurgioes · 2023Article
- Antibiotic cement plate composite structure internal fixation after debridement of bone infection.Scientific reports · 2021Article
- The top three unanswered questions in the management of open fractures.OTA international : the open access journal of orthopaedic trauma · 2020Article
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6 authors.
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Abstract
backgroundLocal antibiotic therapy has gained increasing attraction in the prevention and treatment of fracture infection. However, no reports have used local antibiotic therapy in the management of early infection after fracture fixation with retention of implants.
methodsThe present surgical technique report the use of antibiotic impregnated bone cement in the management of early infection after fracture fixation. Initially, the fractures were fixed with plates. The average time from initial procedure to debridement was15 days (range 9 to 25 days). The infections were treated with irrigation, debridement, and retention of the implant. The lateral surface of the plates was coated with antibiotic cement and the bone defect was filled with antibiotic cement spacer after thorough debridement.
resultsTen patients underwent this technique. The mean follow-up was 2.0 years (range 6 months to 4 years). The bone union rate was 100%, and the average time to bone healing was5.5 months.There was recurrence of infection in one patient before bone healing, but the implants were left in place until bone healed, and the infection was eradicated after implant removal.
conclusionCoating the plate with antibiotic cement is a simple technique which may play a role in the management of early infection after fracture fixation.
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