Evidence map›Paper›PMID 30301404›Full record

ReviewChannels (Austin, Tex.)2018

Potassium channels in the sinoatrial node and their role in heart rate control.

Qadeer Aziz, Yiwen Li, Andrew Tinker

Open access · goldAbstract readReview
In one paragraph

Review in Channels (Austin, Tex.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Guideline
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  7. Aging and sinus node dysfunction: mechanisms and future directions.Clinical science (London, England : 1979) · 2025
    Review
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  11. Review
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  14. Article
  15. Article
  16. Kir6.1 and SUR2B in Cantú syndrome.American journal of physiology. Cell physiology · 2022
    Review
  17. Review
  18. Review
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Qadeer Aziza William Harvey Heart Centre, Barts & The London School of Medicine & Dentistry , Queen Mary, University of London , London , UK.
Yiwen Lia William Harvey Heart Centre, Barts & The London School of Medicine & Dentistry , Queen Mary, University of London , London , UK.
Andrew Tinkera William Harvey Heart Centre, Barts & The London School of Medicine & Dentistry , Queen Mary, University of London , London , UK.
Queen Mary University of London · GB

Funding

AUTOREGULATION OF HINDLIMB BLOOD FLOWK04HL001515 · NHLBI · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI BRITTON, STEVEN LOYAL · 1985 to 1989
–
British Heart Foundation RG/15/15/31742
6 · The paper itself

Abstract

Potassium currents determine the resting membrane potential and govern repolarisation in cardiac myocytes. Here, we review the various currents in the sinoatrial node focussing on their molecular and cellular properties and their role in pacemaking and heart rate control. We also describe how our recent finding of a novel ATP-sensitive potassium channel population in these cells fits into this picture.

Indexed as

AnimalsHeart RateHumansPotassium ChannelsSinoatrial NodePotassium ChannelsATP-sensitive potassium channelheart ratepacemakingpotassium channelsinoatrial node

Identifiers

PMID30301404
PMCPMC6207292
OpenAlexW2896664090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.