Evidence map›Paper›PMID 30301264›Full record

ArticleMolecules (Basel, Switzerland)2018

Synthesis and Biological Evaluation of Novel Indole-Derived Thioureas.

Giuseppina Sanna, Silvia Madeddu, Gabriele Giliberti, Sandra Piras, Marta Struga, Małgorzata Wrzosek, Grażyna Kubiak-Tomaszewska, Anna E Koziol, Oleksandra Savchenko, Tadeusz Lis and 4 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Recent Advances in Nitrogen-Containing Heterocyclic Scaffolds as Antiviral Agents.Medicinal chemistry (Shariqah (United Arab Emirates)) · 2024
    Pooled it
  2. Article
  3. Article
  4. Recent Development of DNA Gyrase Inhibitors: An Update.Mini reviews in medicinal chemistry · 2024
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Giuseppina SannaDepartment of Biomedical Science, University of Cagliari, 09042 Monserrato, Italy. g.sanna@unica.it.ORCID 0000-0002-3999-4263
Silvia MadedduDepartment of Biomedical Science, University of Cagliari, 09042 Monserrato, Italy. silvia.madeddu@unica.it.
Gabriele GilibertiDepartment of Biomedical Science, University of Cagliari, 09042 Monserrato, Italy. ggiliberti@unica.it.
Sandra PirasDepartment of Chemistry and Pharmacy, University of Sassari, 07100 Sassari, Italy. piras@uniss.it.
Marta StrugaChair and Department of Biochemistry, First Faculty of Medicine, Medical University, 02-097 Warszawa, Poland. mstruga@wum.edu.pl.
Małgorzata WrzosekLaboratory of Centre for Preclinical Research, Medical University of Warsaw, 02-097 Warsaw, Poland. malgorzata.wrzosek@wum.edu.pl.
Grażyna Kubiak-TomaszewskaDepartment of Biochemistry and Pharmacogenomics, Faculty of Pharmacy, Medical University of Warsaw, 02-097 Warsaw, Poland. grazyna.kubiak-tomaszewska@wum.edu.pl.
Anna E KoziolFaculty of Chemistry, Maria Curie-Sklodowska University, 20-031 Lublin, Poland. anna.koziol@poczta.umcs.lublin.pl.
Oleksandra SavchenkoFaculty of Chemistry, Maria Curie-Sklodowska University, 20-031 Lublin, Poland. oleksandra.savchenko@poczta.umcs.lublin.pl.
Tadeusz LisFaculty of Chemistry, Univeristy of Wrocław, 50-383 Wrocław, Poland. tadeusz.lis@chem.uni.wroc.pl.
Joanna StefanskaDepartment of Pharmaceutical Microbiology, Medical University, 02-007 Warszawa, Poland. joanna.stefanska@wum.edu.pl.
Piotr TomaszewskiDepartment of Biochemistry, Second Faculty of Medicine, Medical University of Warsaw, 02-097 Warszawa, Poland. piotr.tomaszewski@wum.edu.pl.
Michał SkrzyckiDepartment of Biochemistry, Second Faculty of Medicine, Medical University of Warsaw, 02-097 Warszawa, Poland. mskrzycki@wum.edu.pl.
Daniel SzulczykChair and Department of Biochemistry, First Faculty of Medicine, Medical University, 02-097 Warszawa, Poland. daniel.szulczyk@wum.edu.pl.
Medical University of Warsaw · PLUniversity of Cagliari · ITMaria Curie-Skłodowska University · PLUniversity of Sassari · ITUniversity of Wrocław · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of 2-(1

Indexed as

Anti-Bacterial AgentsCrystallography, X-RayDNA GyraseDNA Topoisomerase IVHumansIndolesMicrobial Sensitivity TestsMolecular StructureStaphylococcus aureusThioureaTopoisomerase II InhibitorsAnti-Bacterial AgentsDNA GyraseDNA Topoisomerase IVIndolesThioureaTopoisomerase II Inhibitorsantibacterial activityanti-HIV activityantiviral activitythiourea derivatives of indoletopoisomerase

Identifiers

PMID30301264
PMCPMC6222422
OpenAlexW2894640248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.