ArticleNutrients2018
The Significance of Low Titre Antigliadin Antibodies in the Diagnosis of Gluten Ataxia.
Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Pooled it
- Neurological Manifestations of Neuropathy and Ataxia in Celiac Disease: A Systematic Review.Nutrients · 2019Pooled it
- Presumptive paroxysmal dyskinesia in 41 dogs: is the diet change enough?Journal of veterinary internal medicine · 2026Article
- Letter to editors regarding "Serological analysis of gluten‑related antibodies in idiopathic neuropathies and cerebellar ataxia".Journal of neurology · 2025Article
- Serological analysis of gluten-related antibodies in idiopathic neuropathies and cerebellar ataxia.Journal of neurology · 2025Article
- Unraveling the Immunopathological Landscape of Celiac Disease: A Comprehensive Review.International journal of molecular sciences · 2023Review
- Celiac Disease and Neurological Manifestations: From Gluten to Neuroinflammation.International journal of molecular sciences · 2022Review
- Cerebellar Abnormalities on Proton MR Spectroscopy and Imaging in Patients With Gluten Ataxia: A Pilot Study.Frontiers in human neuroscience · 2022Article
- Nutrition in Patients with Lactose Malabsorption, Celiac Disease, and Related Disorders.Nutrients · 2021Review
- A serial SPECT-CT study in a celiac disease patient with cerebellar ataxia and psychiatric symptoms.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Article
- Neurological manifestation of coeliac disease with particular emphasis on gluten ataxia and immunological injury: a review article.Gastroenterology and hepatology from bed to bench · 2021Review
- Treatment of Primary Autoimmune Cerebellar Ataxia with Mycophenolate.Cerebellum (London, England) · 2020Article
- Brain fog and non-coeliac gluten sensitivity: Proof of concept brain MRI pilot study.PloS one · 2020Article
- Celiac Disease: Extraintestinal Manifestations and Associated Conditions.Journal of clinical gastroenterology · 2020Review
- Gluten-Induced Extra-Intestinal Manifestations in Potential Celiac Disease-Celiac Trait.Nutrients · 2019Review
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with gluten ataxia (GA) without enteropathy have lower levels of antigliadin antibodies (AGA) compared to patients with coeliac disease (CD). Magnetic Resonance Spectroscopy (NAA/Cr area ratio) of the cerebellum improves in patients with GA following a strict gluten-free diet (GFD). This is associated with clinical improvement. We present our experience of the effect of a GFD in patients with ataxia and low levels of AGA antibodies measured by a commercial assay.
methodsConsecutive patients with ataxia and serum AGA levels below the positive cut-off for CD but above a re-defined cut-off in the context of GA underwent MR spectroscopy at baseline and after a GFD.
resultsTwenty-one consecutive patients with GA were included. Ten were on a strict GFD with elimination of AGA, 5 were on a GFD but continued to have AGA, and 6 patients did not go on a GFD. The NAA/Cr area ratio from the cerebellar vermis increased in all patients on a strict GFD, increased in only 1 out of 5 (20%) patients on a GFD with persisting circulating AGA, and decreased in all patients not on a GFD.
conclusionPatients with ataxia and low titres of AGA benefit from a strict GFD. The results suggest an urgent need to redefine the serological cut-off for circulating AGA in diagnosing GA.
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