ReviewPharmaceuticals (Basel, Switzerland)2018
Gut Microbiota and Iron: The Crucial Actors in Health and Disease.
Review in Pharmaceuticals (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 162 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
162 citing papers in PubMed, 2 syntheses or guidelines pooled it, 294 citations in OpenAlex.
- Arthrospira platensis and Chlorella vulgaris Consumption on Iron Status: A Systematic Review of In Vivo Studies.Molecular nutrition & food research · 2025Pooled it
- The relationship between thyroid and human-associated microbiota: A systematic review of reviews.Reviews in endocrine & metabolic disorders · 2024Pooled it
- Impact of dietary protein quantity on the non-dysbiotic human microbiome: a controlled feeding study.Scientific reports · 2026Trial
- Trial
- Review
- Article
- Iron, Tuberculosis, and Particle-Related Exposures Including Smoking.Pathogens (Basel, Switzerland) · 2026Review
- Relative bioavailability of dietary iron sources in growing Japanese quail: Multi-endpoint dose-response and Random Forest analyses.Poultry science · 2026Article
- Obesity and Iron Metabolism: Mechanisms, Status Assessment, and Clinical Implications.Current obesity reports · 2026Review
- A review of the iron requirements and its determination in commercial poultry.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Review
- The Gut-Iron-Immune Axis in Severe Anaemia and Bacteraemia.Nutrients · 2026Review
- Review
- Review
- Widespread adhesion and iron acquisition traits in Escherichia coli strains obtained from irritable bowel syndrome (IBS) patients.BMC research notes · 2026Article
- Pharmacomicrobiomics of Non-Antibiotic Drugs: Mechanisms and Clinical Consequences of Gut Microbiota Alterations.Pharmaceutics · 2026Review
- Effects of Traditional Chinese Herbal Extracts on Tear Staining, Iron Status, Immune Function, and Antioxidant Capacity in Dogs.Animals : an open access journal from MDPI · 2026Article
- Early-Life Iron Exposure Influences Long-Term Gut Microbiota Recovery After Intestinal Dysbiosis.Microorganisms · 2026Article
- Time-of-day difference in iron supplementation in iron-deficient pregnant model mice.NPJ science of food · 2026Article
- Impact of Encapsulated Iron Availability on the Growth Kinetics ofPathogens (Basel, Switzerland) · 2026Article
- An Engineered Variant ofACS synthetic biology · 2026Article
102 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Iron (Fe) is a highly ample metal on planet earth (~35% of the Earth's mass) and is particularly essential for most life forms, including from bacteria to mammals. Nonetheless, iron deficiency is highly prevalent in developing countries, and oral administration of this metal is so far the most effective treatment for human beings. Notably, the excessive amount of unabsorbed iron leave unappreciated side effects at the highly interactive host⁻microbe interface of the human gastrointestinal tract. Recent advances in elucidating the molecular basis of interactions between iron and gut microbiota shed new light(s) on the health and pathogenesis of intestinal inflammatory diseases. We here aim to present the dynamic modulation of intestinal microbiota by iron availability, and conversely, the influence on dietary iron absorption in the gut. The central part of this review is intended to summarize our current understanding about the effects of luminal iron on host⁻microbe interactions in the context of human health and disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.