Evidence map›Paper›PMID 30300940›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2018

5-Oxyacetic Acid Modification Destabilizes Double Helical Stem Structures and Favors Anionic Watson-Crick like cmo

Elisabeth Strebitzer, Atul Rangadurai, Raphael Plangger, Johannes Kremser, Michael Andreas Juen, Martin Tollinger, Hashim M Al-Hashimi, Christoph Kreutz

Open access · hybridAbstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The Tautomeric State ofACS central science · 2024
    Article
  5. Article
  6. Article
  7. Measuring thermodynamic preferences to form non-native conformations in nucleic acids using ultraviolet melting.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. The multiple flavors of GoU pairs in RNA.Journal of molecular recognition : JMR · 2019
    Review
  14. The roles of structural dynamics in the cellular functions of RNAs.Nature reviews. Molecular cell biology · 2019
    Review
  15. Base-pair Opening Dynamics of Nucleic Acids in Relation to Their Biological Function.Computational and structural biotechnology journal · 2019
    Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Elisabeth StrebitzerInstitute of Organic Chemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80/82, 6020, Innsbruck, Austria.
Atul RangaduraiDepartment of Biochemistry and Department of Chemistry, Duke University School of Medicine, Nanaline H. Duke Building, 307 Research Drive, Durham, NC, 27710, USA.
Raphael PlanggerInstitute of Organic Chemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80/82, 6020, Innsbruck, Austria.
Johannes KremserInstitute of Organic Chemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80/82, 6020, Innsbruck, Austria.
Michael Andreas JuenInstitute of Organic Chemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80/82, 6020, Innsbruck, Austria.
Martin TollingerInstitute of Organic Chemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80/82, 6020, Innsbruck, Austria.
Hashim M Al-HashimiDepartment of Biochemistry and Department of Chemistry, Duke University School of Medicine, Nanaline H. Duke Building, 307 Research Drive, Durham, NC, 27710, USA.
Christoph KreutzInstitute of Organic Chemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80/82, 6020, Innsbruck, Austria.ORCID http://orcid.org/0000-0002-7018-9326
Universität Innsbruck · ATDuke University · US

Funding

Role of DNA structural dynamics in mutagenesis and oncogenesisR01GM089846 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Hashim M Al-Hashimi · 2010 to 2026
$5.2M
NIGMS NIH HHS R01 GM089846NIH HHS RO1 GM089846
6 · The paper itself

Abstract

Watson-Crick like G-U mismatches with tautomeric G

Indexed as

NMR spectroscopyrelaxation dispersionRNARNA modifications

Identifiers

PMID30300940
PMCPMC6348377
OpenAlexW2897222589

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.