Evidence map›Paper›PMID 30299584›Full record

ArticleJournal of cellular and molecular medicine2018

Activation of transient receptor potential vanilloid 3 channel (TRPV3) aggravated pathological cardiac hypertrophy via calcineurin/NFATc3 pathway in rats.

Qianhui Zhang, Hanping Qi, Yonggang Cao, Pilong Shi, Chao Song, Lina Ba, Yunping Chen, Jingquan Gao, Shuzhi Li, Baiyan Li and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. A detailed review of pharmacology of MFN1 (mitofusion-1)-mediated mitochondrial dynamics: Implications for cellular health and diseases.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Review
  7. Review
  8. Review
  9. Article
  10. TRPV3: Structure, Diseases and Modulators.Molecules (Basel, Switzerland) · 2023
    Review
  11. Review
  12. Article
  13. Article
  14. Neutrophil-like cell membrane-coated siRNA of lncRNAMolecular therapy. Nucleic acids · 2022
    Article
  15. Article
  16. Review
  17. MicroRNA-369 attenuates hypoxia-induced cardiomyocyte apoptosis and inflammation via targeting TRPV3.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2021
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Qianhui ZhangDepartment of Pharmacology, Harbin Medical University-Daqing, Daqing, Heilongjiang, China.
Hanping QiDepartment of Pharmacology, Harbin Medical University-Daqing, Daqing, Heilongjiang, China.
Yonggang CaoDepartment of Pharmacology, Harbin Medical University-Daqing, Daqing, Heilongjiang, China.
Pilong ShiDepartment of Pharmacology, Harbin Medical University-Daqing, Daqing, Heilongjiang, China.
Chao SongDepartment of Pharmacology, Harbin Medical University-Daqing, Daqing, Heilongjiang, China.
Lina BaDepartment of Pharmacology, Harbin Medical University-Daqing, Daqing, Heilongjiang, China.
Yunping ChenDepartment of Pharmacology, Harbin Medical University-Daqing, Daqing, Heilongjiang, China.
Jingquan GaoDepartment of Nursing, Harbin Medical University-Daqing, Daqing, Heilongjiang, China.
Shuzhi LiDepartment of Pharmacology, Harbin Medical University-Daqing, Daqing, Heilongjiang, China.
Baiyan LiDepartment of Pharmacology, Harbin Medical University, Harbin, Heilongjiang, China.
Hongli SunDepartment of Pharmacology, Harbin Medical University-Daqing, Daqing, Heilongjiang, China.ORCID 0000-0002-8186-2344
Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac hypertrophy is a compensatory response to mechanical stimuli and neurohormonal factors, ultimately progresses to heart failure. The proteins of some transient receptor potential (TRP) channels, Ca

Indexed as

AnimalsCalcineurinCalcium-Calmodulin-Dependent Protein Kinase Type 2CardiomegalyCymenesDisease Models, AnimalGene Expression RegulationHeart FailureHumansMonoterpenesMyocytes, CardiacNFATC Transcription FactorsRatsSignal TransductionSwimmingTRPV Cation ChannelsCalcineurinCalcium-Calmodulin-Dependent Protein Kinase Type 2carvacrolCymenesMonoterpenesNFATC Transcription Factorstranscription factor NF-AT c3TRPV3 protein, ratTRPV Cation ChannelsCa2+CalcineurinCardiac HypertrophyNFATc3Transient receptor potential vanilloid 3

Identifiers

PMID30299584
PMCPMC6237578
OpenAlexW2895782699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.