Evidence map›Paper›PMID 30299256›Full record

ArticleeLife2018

Transition between fermentation and respiration determines history-dependent behavior in fluctuating carbon sources.

Bram Cerulus, Abbas Jariani, Gemma Perez-Samper, Lieselotte Vermeersch, Julian Mj Pietsch, Matthew M Crane, Aaron M New, Brigida Gallone, Miguel Roncoroni, Maria C Dzialo and 8 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 62 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 3 countries.

Bram Cerulus *VIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, Belgium.
Abbas Jariani *VIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, Belgium.ORCID http://orcid.org/0000-0003-2715-933X
Gemma Perez-SamperVIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, Belgium.
Lieselotte VermeerschVIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, Belgium.ORCID http://orcid.org/0000-0001-5789-2220
Julian Mj PietschCentre for Synthetic and Systems Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.ORCID https://orcid.org/0000-0002-9992-2384
Matthew M CraneCentre for Synthetic and Systems Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Aaron M NewVIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, Belgium.
Brigida GalloneVIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, Belgium.
Miguel RoncoroniVIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, Belgium.
Maria C DzialoVIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, Belgium.
Sander K GoversVIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, Belgium.ORCID http://orcid.org/0000-0003-0260-4054
Jhana O HendrickxVIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, Belgium.
Eva GalleVIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, Belgium.
Maarten CoomansVIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, Belgium.
Pieter BerdenVIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, Belgium.
Sara VerbandtVIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, Belgium.
Peter S SwainCentre for Synthetic and Systems Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.ORCID http://orcid.org/0000-0001-7489-8587
Kevin J VerstrepenVIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, Belgium.ORCID http://orcid.org/0000-0002-3077-6219
VIB-KU Leuven Center for Microbiology · BEUniversity of Edinburgh · GBGhent University · BEUniversity of Washington · US

Funding

European Research Council CoG682009European Research Counsil CoG682009Human Frontier Science Program 246 RGP0050/2013
6 · The paper itself

Abstract

Cells constantly adapt to environmental fluctuations. These physiological changes require time and therefore cause a lag phase during which the cells do not function optimally. Interestingly, past exposure to an environmental condition can shorten the time needed to adapt when the condition re-occurs, even in daughter cells that never directly encountered the initial condition. Here, we use the molecular toolbox of

Indexed as

FermentationAerobiosisCarbohydratesCarbonCell CountCell NucleusGene Expression ProfilingGene Expression Regulation, FungalGene Regulatory NetworksGenes, FungalMutationOxygen ConsumptionRNA, MessengerSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTime FactorsCarbohydratesCarbonRNA, MessengerSaccharomyces cerevisiae Proteinscellular memorycomputational biologygene regulationglucose repressioninfectious diseaselag phasemetabolic shiftmicrobiologyS. cerevisiaesingle-cell analysissystems biology

Identifiers

PMID30299256
PMCPMC6211830
OpenAlexW2897377645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.