ArticleeLife2018
Range, routing and kinetics of rod signaling in primate retina.
Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed.
- Spatially local inhibition and synaptic plasticity together enable dynamic, context-dependent integration of parallel sensory pathways.Cell reports · 2026Article
- Article
- Spatially-local inhibition and synaptic plasticity together enable dynamic, context-dependent integration of parallel sensory pathways.bioRxiv : the preprint server for biology · 2025Article
- Divergent mechanisms of neural adaptation and instability in the mammalian retina.Current biology : CB · 2025Article
- Temporal Transformation of the Rod Single-Photon Response in the Retinal Circuitry.Investigative ophthalmology & visual science · 2025Article
- What can the eye see with melanopsin?Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Ambient lighting alters pattern electroretinogram P50 peak time and spatial sensitivity.Documenta ophthalmologica. Advances in ophthalmology · 2024Article
- Biophysical neural adaptation mechanisms enable artificial neural networks to capture dynamic retinal computation.Nature communications · 2024Article
- Primate retina trades single-photon detection for high-fidelity contrast encoding.Nature communications · 2024Article
- Cone-Driven, Geniculocortical Responses in Canine Models of Outer Retinal Disease.Translational vision science & technology · 2024Article
- Cone-driven, geniculo-cortical responses in canine models of outer retinal disease.bioRxiv : the preprint server for biology · 2023Article
- Regional variation in the organization and connectivity of the first synapse in the primate night vision pathway.iScience · 2023Article
- Using optogenetics to dissect rod inputs to OFF ganglion cells in the mouse retina.Frontiers in ophthalmology · 2023Article
- Rod-cone signal interference in the retina shapes perception in primates.Frontiers in ophthalmology · 2023Article
- Calcium-permeable AMPA receptors on AII amacrine cells mediate sustained signaling in the On-pathway of the primate retina.Cell reports · 2022Article
- Vision: Life on the dark side.Current biology : CB · 2022Article
- Multiple Invagination Patterns and Synaptic Efficacy in Primate and Mouse Rod Synaptic Terminals.Investigative ophthalmology & visual science · 2022Article
- Divergent outer retinal circuits drive image and non-image visual behaviors.Cell reports · 2022Article
- Cone-Driven Retinal Responses Are Shaped by Rod But Not Cone HCN1.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- A hyperpolarizing rod bipolar cell in the sea lamprey, Petromyzon marinus.The Journal of experimental biology · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Stimulus- or context-dependent routing of neural signals through parallel pathways can permit flexible processing of diverse inputs. For example, work in mouse shows that rod photoreceptor signals are routed through several retinal pathways, each specialized for different light levels. This light-level-dependent routing of rod signals has been invoked to explain several human perceptual results, but it has not been tested in primate retina. Here, we show, surprisingly, that rod signals traverse the primate retina almost exclusively through a single pathway - the dedicated rod bipolar pathway. Identical experiments in mouse and primate reveal substantial differences in how rod signals traverse the retina. These results require reevaluating human perceptual results in terms of flexible computation within this single pathway. This includes a prominent speeding of rod signals with light level - which we show is inherited directly from the rod photoreceptors themselves rather than from different pathways with distinct kinetics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.