ArticleExperimental physiology2019
Ventilatory constraints influence physiological dead space in heart failure.
Article in Experimental physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Ventilatory limitation to exercise in patients with HFpEF and obesity: No room to breathe.Respiratory physiology & neurobiology · 2026Trial
- Consequences of group III/IV afferent feedback and respiratory muscle work on exercise tolerance in heart failure with reduced ejection fraction.Experimental physiology · 2023Review
- Higher Work of Breathing During Exercise in Heart Failure With Preserved Ejection Fraction.Chest · 2023Article
- Effects of exertional dyspnea on early mobilization of patients with acute decompensated heart failure.Journal of physical therapy science · 2022Article
- Influence of locomotor muscle group III/IV afferents on cardiovascular and ventilatory responses in human heart failure during submaximal exercise.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Resting Physiologic Dead Space as Predictor of Postoperative Pulmonary Complications After Robotic-Assisted Lung Resection: A Pilot Study.Frontiers in physiology · 2022Article
- Exercise training decreases intercostal and transversus abdominis muscle blood flows in heart failure rats during submaximal exercise.Respiratory physiology & neurobiology · 2021Article
- Respiratory muscle work influences locomotor convective and diffusive oxygen transport in human heart failure during exercise.Physiological reports · 2020Article
- Metabo- and mechanoreceptor expression in human heart failure: Relationships with the locomotor muscle afferent influence on exercise responses.Experimental physiology · 2020Article
- Carotid chemoreflex and muscle metaboreflex interact to the regulation of ventilation in patients with heart failure with reduced ejection fraction.Physiological reports · 2020Article
- Impaired central hemodynamics in chronic obstructive pulmonary disease during submaximal exercise.Journal of applied physiology (Bethesda, Md. : 1985) · 2019Article
- Exercise Ventilatory Efficiency in Older and Younger Heart Failure Patients With Preserved Ejection Fraction.Journal of cardiac failure · 2019Article
- Morphine May Contribute to Improving Respiratory Failure in Severe COVID-19: A Case Report.Indian journal of palliative careArticle
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
2 authors.
Funding
Abstract
NEW
findingsWhat is the central question of this study? The goal of this study was to investigate the effect of alterations in tidal volume and alveolar volume on the elevated physiological dead space and the contribution of ventilatory constraints thereof in heart failure patients during submaximal exercise. What is the main finding and its importance? We found that physiological dead space was elevated in heart failure via reduced tidal volume and alveolar volume. Furthermore, the degree of ventilatory constraints was associated with physiological dead space and alveolar volume. ABSTRACT: Patients who have heart failure with reduced ejection fraction (HFrEF) exhibit impaired ventilatory efficiency [i.e. greater ventilatory equivalent for carbon dioxide (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.