Evidence map›Paper›PMID 30298804›Full record

ReviewThe American journal of tropical medicine and hygiene2018

Taking Sharper Pictures of Malaria with CAMERAs: Combined Antibodies to Measure Exposure Recency Assays.

Bryan Greenhouse, David L Smith, Isabel Rodríguez-Barraquer, Ivo Mueller, Chris J Drakeley

Abstract readReview
In one paragraph

Review in The American journal of tropical medicine and hygiene, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. PvMSP8 as a NovelPathogens (Basel, Switzerland) · 2021
    Article
  14. Article
  15. Antibody Profiles toThe American journal of tropical medicine and hygiene · 2020
    Article
  16. Article
  17. Observational
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bryan GreenhouseDepartment of Medicine, University of California, San Francisco, San Francisco, California.
David L SmithInstitute for Health Metrics and Evaluation, University of Washington, Seattle, Washington.
Isabel Rodríguez-BarraquerDepartment of Medicine, University of California, San Francisco, San Francisco, California.
Ivo MuellerInstitute Pasteur, Paris, France.
Chris J DrakeleyLondon School of Hygiene & Tropical Medicine, London, United Kingdom.

Funding

Transmission ProjectU19AI089674 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MATTHEW G DORSEY, MOSES Robert KAMYA · 2010 to 2026
$29.3M
Understanding, tracking and eliminating malaria transmission in the Asia - Pacific RegionU19AI129392 · NIAID · WALTER AND ELIZA HALL INST MEDICAL RES · PI Ivo J Mueller, Leanne Robinson · 2017 to 2026
$7.1M
Novel serologic assays of P. falciparum exposure for improved surveillance in control and elimination.R01AI119019 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GREENHOUSE, BRYAN R · 2016 to 2020
$2.7M
NIAID NIH HHS R01 AI119019NIAID NIH HHS U19 AI089674NIAID NIH HHS U19 AI129392
6 · The paper itself

Abstract

Antibodies directed against malaria parasites are easy and inexpensive to measure but remain an underused surveillance tool because of a lack of consensus on what to measure and how to interpret results. High-throughput screening of antibodies from well-characterized cohorts offers a means to substantially improve existing assays by rationally choosing the most informative sets of responses and analytical methods. Recent data suggest that high-resolution information on malaria exposure can be obtained from a small number of samples by measuring a handful of properly chosen antibody responses. In this review, we discuss how standardized multi-antibody assays can be developed and efficiently integrated into existing surveillance activities, with potential to greatly augment the breadth and quality of information available to direct and monitor malaria control and elimination efforts.

Indexed as

Antibodies, ProtozoanAntibody FormationAntigens, ProtozoanEpidemiological MonitoringHumansMalariaPlasmodium falciparumSerologic TestsAntibodies, ProtozoanAntigens, Protozoan

Identifiers

PMID30298804
PMCPMC6221205

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.