Evidence map›Paper›PMID 30298371›Full record

Trial reportJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2020

Agreement between left ventricular ejection fraction assessed in patients with gated IQ-SPECT and conventional imaging.

Lucia Leva, Roberta Matheoud, Gianmauro Sacchetti, Alessandro Carriero, Marco Brambilla

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. New hardware, new software, different results: The estimation of left ventricular volumes and ejection fractions with gated myocardial perfusion SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Lucia LevaDepartment of Nuclear Medicine, University Hospital 'Maggiore della Carità', Novara, Italy.
Roberta MatheoudDepartment of Medical Physics, University Hospital 'Maggiore della Carità', Novara, Italy.
Gianmauro SacchettiDepartment of Nuclear Medicine, University Hospital 'Maggiore della Carità', Novara, Italy.
Alessandro CarrieroDepartment of Radiology, University Hospital 'Maggiore della Carità', Novara, Italy.
Marco BrambillaDepartment of Medical Physics, University Hospital 'Maggiore della Carità', Novara, Italy. marco.brambilla@maggioreosp.novara.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of the study was to assess the agreement between the left ventricular ejection fraction (LVEF) values obtained with IQ-SPECT and those obtained with a conventional gamma camera equipped with low-energy high-resolution (LEHR), considered as the method of reference.

methodsGated-stress MPI using 99mTc-tetrofosmin was performed in 55 consecutive patients. The patients underwent two sequential acquisitions (Method A and B) performed on Symbia-IQ SPECT with different acquisition times and one (Method C) on a Ecam SPECT equipped with LEHR collimators. The values of the different datasets were compared using the Bland-Altman analysis method: the bias and the limits of agreement (LA) were estimated in a head-to-head comparison of the three protocols.

resultsIn the (Method A-Method C) comparison for LVEF, the bias was 3.8% and the LAs ranged from - 9.3% to 16.8%. The agreement was still lower between Method B and C, whilst only slightly improved when Methods A and B were compared.

conclusionsThe wide amplitude in LA intervals of about 30% indicates that IQ and LEHR GSPECT are not interchangeable. The values obtained with IQ-SPECT should only be used with caution when evaluating the functional state of the heart.

Indexed as

AdultAgedAged, 80 and overAlgorithmsCardiac-Gated Single-Photon Emission Computer-Assisted TomographyCoronary Artery DiseaseFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedMyocardial Perfusion ImagingOrganophosphorus CompoundsOrganotechnetium CompoundsRadiopharmaceuticalsReproducibility of ResultsOrganophosphorus CompoundsOrganotechnetium CompoundsRadiopharmaceuticalstechnetium tc-99m tetrofosminCADgated SPECTinstrumentationperfusion agentsstatistical analysis

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.