Evidence map›Paper›PMID 30298359›Full record

ArticleGenes & genomics2019

Functional evaluation of alternative splicing in the FAM190A gene.

Sung Ung Kang, Joon Tae Park

Abstract read
PubMed Publisher
In one paragraph

Article in Genes & genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Polymorphisms ofFoods (Basel, Switzerland) · 2023
    Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Sung Ung KangInstitute of Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Joon Tae ParkDivision of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon, 22012, South Korea. joontae.park@inu.ac.kr.ORCID http://orcid.org/0000-0003-2396-9108
Incheon National University · KRJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human FAM190A gene undergoes frequent alteration in human cancer, most commonly involving in-frame deletions in exon 9 or exons 9 & 10. These deletions form novel peptide sequences, serving as presumptive cancer-specific neo antigens. However, it remains elusive whether these in-frame deletions of FAM190A could induce oncogenic properties in vivo. In this study, we aimed to explore the functional significance of in-frame deletions in FAM190A genes. We generated two deletion mutant forms, FAM190A

Indexed as

Alternative Splicing3T3 CellsAnimalsCarcinogenesisCell Cycle ProteinsFemaleGain of Function MutationMiceMice, NudeOncogene ProteinsCCSER1 protein, humanCell Cycle ProteinsOncogene ProteinsAlternative splicingFAM190AGain-of-functionNeo antigensXenograft

Identifiers

PMID30298359
OpenAlexW2897438107

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.