Evidence map›Paper›PMID 30298346›Full record

GuidelineThe journal of headache and pain2018

European headache federation guideline on idiopathic intracranial hypertension.

Jan Hoffmann, Susan P Mollan, Koen Paemeleire, Christian Lampl, Rigmor H Jensen, Alexandra J Sinclair

Registry-linked trialAbstract readPractice Guideline
In one paragraph

Guideline in The journal of headache and pain, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06913712 (Evolution of Body Mass Index in Idiopathic Intracranial Hypertension and Its Relationship With the Response to Treatment. Retrospective and Prospective Study), which is not on this map. Cited by 95 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06913712 recruitingnot on this mapstarted 2024, after this paper: background citation

Evolution of Body Mass Index in Idiopathic Intracranial Hypertension and Its Relationship With the Response to Treatment. Retrospective and Prospective Study

TypeobservationalSponsorUniversity of ValenciaRan2024 to 2028Enrolled25ConditionsIdiopathic Intracranial Hypertension (IIH)ArmsWeight loss without pharmacotherapy
3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Therapeutic role of GLP-1 receptor agonists in idiopathic intracranial hypertension: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Pooled it
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  20. Idiopathic CSF dynamic disturbances causing headache: a narrative review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review

35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jan HoffmannBasic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, Wellcome Foundation Building, Denmark Hill Campus, King's College London, London, SE5 9PJ, UK. jan.hoffmann@kcl.ac.uk.ORCID http://orcid.org/0000-0002-2103-9081
Susan P MollanBirmingham Neuro-Ophthalmology, University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital, Birmingham, UK.
Koen PaemeleireDepartment of Neurology, Ghent University Hospital, Ghent, Belgium.
Christian LamplHeadache Medical Centre, Seilerstaette Linz, Ordensklinikum Linz, Barmherzige Schwestern, Linz, Austria.
Rigmor H JensenDanish Headache Center, Department of Neurology, Rigshospitalet-Glostrup, University of Copenhagen, Glostrup, Denmark.
Alexandra J SinclairMetabolic Neurology, Institute of Metabolism and Systems Research, University of Birmingham, Edgbaston, UK.

Funding

Department of Health NIHR-CS-011-028Medical Research Council MR/K015184/1National Institute for Health Research NIHR-CS-011-028
6 · The paper itself

Abstract

backgroundIdiopathic Intracranial Hypertension (IIH) is characterized by an elevation of intracranial pressure (ICP no identifiable cause. The aetiology remains largely unknown, however observations made in a number of recent clinical studies are increasing the understanding of the disease and now provide the basis for evidence-based treatment strategies.

methodsThe Embase, CDSR, CENTRAL, DARE and MEDLINE databases were searched up to 1st June 2018. We analyzed randomized controlled trials and systematic reviews that investigate IIH.

resultsDiagnostic uncertainty, headache morbidity and visual loss are among the highest concerns of clinicians and patients in this disease area. Research in this field is infrequent due to the rarity of the disease and the lack of understanding of the underlying pathology.

conclusionsThis European Headache Federation consensus paper provides evidence-based recommendations and practical advice on the investigation and management of IIH.

Indexed as

HeadacheHumansPseudotumor CerebriRandomized Controlled Trials as Topic

Identifiers

PMID30298346
PMCPMC6755569

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.