ReviewCurrent neurology and neuroscience reports2018
The Impact of Interictal Discharges on Performance.
Review in Current neurology and neuroscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04141332 (Specific Language Impairment), which is not on this map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Specific Language Impairment (SLI) in Children May Caused by Epileptic Brain Activity
Who cites it
11 citing papers in PubMed.
- Effects of temporal lobe seizures on visual recognition memory in a non-human primate model.Epilepsy & behavior : E&B · 2025Article
- The epileptic blip syndrome.Epilepsy & behavior reports · 2024Article
- Magnetoencephalography Imaging Reveals Abnormal Information Flow in Temporal Lobe Epilepsy.Brain connectivity · 2022Article
- A study of brain functional network and alertness changes in temporal lobe epilepsy with and without focal to bilateral tonic-clonic seizures.BMC neurology · 2022Article
- The effect of interictal epileptic discharges and following spindles on motor sequence learning in epilepsy patients.Frontiers in neurology · 2022Article
- Artificial neural network trained on smartphone behavior can trace epileptiform activity in epilepsy.iScience · 2021Article
- Investigating the Effects of Seizures on Procedural Memory Performance in Patients with Epilepsy.Brain sciences · 2021Article
- Sharp-Wave Ripple Frequency and Interictal Epileptic Discharges Increase in Tandem During Thermal Induction of Seizures in a Mouse Model of Genetic Epilepsy.Frontiers in cellular neuroscience · 2021Article
- Concurrent EEG monitoring helps interpret neuropsychological testing results in patients with epilepsy.Epilepsy & behavior : E&B · 2020Article
- Glioma-Induced Alterations in Neuronal Activity and Neurovascular Coupling during Disease Progression.Cell reports · 2020Article
- Association between Interictal Epileptiform Discharges and Autistic Spectrum Disorder.Brain sciences · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewOur purpose is to review evidence relating to the concept that interictal epileptiform discharges (IEDs) impair brain performance. RECENT
findingsSophisticated measures of motor and cognitive performance have clarified older observations, confirming that in both animals and humans, IEDs affect aspects of performance, IED morphology, frequency, anatomical distribution, and duration matter. However, we now know that it is difficult to draw a line between IEDs and seizures, not only by electrical criteria but even by metabolic and molecular measures. IEDs impair performance acutely and probably chronically. Thus, there are good theoretical reasons for suppressing them, but no consensus has been reached on how much effort this deserves. Many antiepileptic medications effective for control of clinical seizures have little effect on IEDs. Better methods of measuring outcomes may allow selection of individual patients for whom treatment aimed at IEDs is worthwhile.
Indexed as
Identifiers
30298240What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.