Evidence map›Paper›PMID 30298127›Full record

ArticleFrontiers in chemistry2018

Protected and De-protected Platinum(IV) Glycoconjugates With GLUT1 and OCT2-Mediated Selective Cancer Targeting: Demonstrated Enhanced Transporter-Mediated Cytotoxic Properties

Jing Ma, Hanfang Liu, Zhuoqing Xi, Jiuzhou Hou, Yingguang Li, Jie Niu, Tong Liu, Shuning Bi, Xin Wang, Chaojie Wang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

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  8. Transporter and protease mediated delivery of platinum complexes for precision oncology.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Jing MaInstitute of Chemical Biology, College of Pharmacy, Henan University, Kaifeng, China.
Hanfang LiuInstitute of Chemical Biology, College of Pharmacy, Henan University, Kaifeng, China.
Zhuoqing XiInstitute of Chemical Biology, College of Pharmacy, Henan University, Kaifeng, China.
Jiuzhou HouInstitute of Chemical Biology, College of Pharmacy, Henan University, Kaifeng, China.
Yingguang LiInstitute of Chemical Biology, College of Pharmacy, Henan University, Kaifeng, China.
Jie NiuInstitute of Chemical Biology, College of Pharmacy, Henan University, Kaifeng, China.
Tong LiuInstitute of Chemical Biology, College of Pharmacy, Henan University, Kaifeng, China.
Shuning BiInstitute of Chemical Biology, College of Pharmacy, Henan University, Kaifeng, China.
Xin WangTianjin Key Laboratory of Molecular Drug Research, State Key Laboratory of Elemento-organic Chemistry, College of Pharmacy, Nankai University, Tianjin, China.
Chaojie WangThe Key Laboratory of Natural Medicine and Immuno-Engineering, Henan University, Kaifeng, China.
Jiajia WangHenan University Joint National Laboratory for Antibody Drug Engineering, School of Basic Medicine Science, Henan University, Kaifeng, China.
Songqiang XieInstitute of Chemical Biology, College of Pharmacy, Henan University, Kaifeng, China.
Peng G WangTianjin Key Laboratory of Molecular Drug Research, State Key Laboratory of Elemento-organic Chemistry, College of Pharmacy, Nankai University, Tianjin, China.
Henan University · CNNankai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physiological characteristics of human malignancies are increased glycolysis and overexpression of glucose transporters (GLUTs).

Indexed as

cancer targetingglucose transporter 1organic cation transporter 2platinum(IV) glycoconjugatestransporter-mediated cytotoxic properties

Identifiers

PMID30298127
PMCPMC6160541
OpenAlexW2891175521

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.