Evidence map›Paper›PMID 30298065›Full record

Trial reportFrontiers in immunology2018

Eliciting Dose and Safety Outcomes From a Large Dataset of Standardized Multiple Food Challenges.

Natasha Purington, R Sharon Chinthrajah, Andrew Long, Sayantani Sindher, Sandra Andorf, Katherine O'Laughlin, Margaret A Woch, Alexandra Scheiber, Amal Assa'ad, Jacqueline Pongracic and 7 more

Abstract readClinical Trial
In one paragraph

Trial report in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Context-dependent regulation of mast cell-mediated food allergy in C57BL/6J mice.The Journal of allergy and clinical immunology · 2026
    Article
  7. Feeding the Skin? Foods in Personal Care Products and the Risk of Allergy.The Journal of clinical and aesthetic dermatology · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. WAO consensus on DEfinition of Food Allergy SEverity (DEFASE).The World Allergy Organization journal · 2023
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Natasha PuringtonSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
R Sharon ChinthrajahSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
Andrew LongSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
Sayantani SindherSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
Sandra AndorfSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
Katherine O'LaughlinSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
Margaret A WochSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
Alexandra ScheiberSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
Amal Assa'adDivision of Allergy and Immunology, Cincinnati Children's Medical Center, Cincinnati, OH, United States.
Jacqueline PongracicDivision of Allergy and Immunology, The Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States.
Jonathan M SpergelDivision of Allergy and Immunology, Department of Pediatrics, The Children's Hospital of Philadelphia, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA, United States.
Jonathan TamDivision of Clinical Immunology and Allergy, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Stephen TillesASTHMA Inc. Clinical Research Center, Northwest Asthma and Allergy Center, University of Washington, Seattle, WA, United States.
Julie WangDivision of Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Stephen J GalliSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
Manisha DesaiSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.
Kari C NadeauSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.

Funding

Tracking allergen specific T cells in multi-food allergyU19AI104209 · NIAID · STANFORD UNIVERSITY · PI GALLI, STEPHEN JOSEPH · 2013 to 2025
$17.3M
NIAID NIH HHS U19 AI104209
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Administration, OralAdolescentAdultAllergensArachisAsthmaChildChild, PreschoolDatasets as TopicFemaleFoodFood HypersensitivityHumansImmunoglobulin EInfantMaleAllergensImmunoglobulin Eadverse eventsdose curvesfood allergyoral food challengesafety outcome

Identifiers

PMID30298065
PMCPMC6160556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.