Evidence map›Paper›PMID 30297990›Full record

ArticleFrontiers in behavioral neuroscience2018

Mice With Partial Deletion of Y-Heterochromatin Exhibits Stress Vulnerability.

Sandeep Kumar Dey, Avijeet Kamle, Ram Reddy Dereddi, Shiju M Thomas, Shashi Rekha Thummala, Arvind Kumar, Sumana Chakravarty, Rachel A Jesudasan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in behavioral neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Satellite DNAs and human sex chromosome variation.Seminars in cell & developmental biology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sandeep Kumar DeyCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Avijeet KamleCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Ram Reddy DereddiCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Shiju M ThomasCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Shashi Rekha ThummalaCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Arvind KumarCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Sumana ChakravartyCSIR-Indian Institute of Chemical Technology, Hyderabad, India.
Rachel A JesudasanCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Centre for Cellular and Molecular Biology · INIndian Institute of Chemical Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of Y chromosome in sex determination and male fertility is well established. It is also known that infertile men are prone to psychological disturbances. Earlier studies in the laboratory identified genes expressed in testes that are putatively regulated by Y chromosome in man and mouse. With the availability of a Y-deleted mouse model, that is subfertile, we studied the effect of a partial deletion of Y-chromosomal heterochromatin on mouse behavior when compared to its wild type. The partial Y-deleted mice exhibited anxiety like phenotype under stress when different anxiety (open field test and elevated plus maze, EPM test) and depression related tests (tail suspension and force swim) were performed. The mutant mice also showed reduction in hippocampal neurogenesis and altered expression of neurogenesis markers such as Nestin,

Indexed as

anxietybehaviorneurogenesisY chromosomal homologyY-deleted mouse

Identifiers

PMID30297990
PMCPMC6160548
OpenAlexW2891728847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.