Evidence map›Paper›PMID 30297977›Full record

ArticleSarcoma2018

Health Care Resource Utilization and Costs among Adult Patients with Advanced Soft Tissue Sarcoma: A Retrospective Medical Record Review in the United Kingdom, Spain, Germany, and France.

Daniel S Mytelka, Saurabh P Nagar, Yulia D'yachkova, Elizabeth M La, James A Kaye, Sean D Candrilli, Bernd Kasper, Jose Antonio Lopez-Martin, Maria Lorenzo

Open access · hybridAbstract read
In one paragraph

Article in Sarcoma, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 5 countries.

Daniel S MytelkaEli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285, USA.ORCID 0000-0001-7669-8634
Saurabh P NagarRTI Health Solutions, 200 Park Offices Drive, Research Triangle Park, NC 27709, USA.
Yulia D'yachkovaEli Lilly Gesellschaft m.b.H., Koelblgasse 8-10, 1030 Vienna, Austria.
Elizabeth M LaRTI Health Solutions, 200 Park Offices Drive, Research Triangle Park, NC 27709, USA.
James A KayeRTI Health Solutions, 307 Waverley Oaks Road, Suite 101, Waltham, MA 02452, USA.
Sean D CandrilliRTI Health Solutions, 200 Park Offices Drive, Research Triangle Park, NC 27709, USA.
Bernd KasperMannheim University Medical Center, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.ORCID 0000-0001-8425-8356
Jose Antonio Lopez-Martin12 de Octubre University Hospital, Avenida de Córdoba, s/n, 28041 Madrid, Spain.
Maria LorenzoEli Lilly and Company Limited, Lilly Research Centre, Erl Wood Manor, Sunninghill Road, Windlesham, Surrey GU20 6PH, UK.
RTI Health Solutions · USEli Lilly (United Kingdom) · GBEli Lilly (United States) · USHeidelberg University · DELudwig Boltzmann Gesellschaft · ATResearch Institute Hospital 12 de Octubre · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe health care resource utilization and costs for patients with advanced soft tissue sarcoma (STS) in the United Kingdom (UK), Spain, Germany, and France.

methodsPhysicians abstracted data for adult patients with a diagnosis of advanced STS (other than Kaposi's sarcoma or gastrointestinal stromal tumor) who received ≥1 lines of systemic therapy. Health care resource utilization related to advanced STS treatment was recorded; associated costs were estimated by applying unit costs.

resultsA total of 130 physicians provided data for 807 patients (UK: 199; Spain: 203; Germany: 204; and France: 201). The site of care during active treatment varied based on differences in the health care systems of these four countries. Total mean per-patient health care cost in the UK was £19,457; in Spain, €26,814; in Germany, €20,468; and in France, €24,368. Advanced STS-related systemic treatment costs were driven primarily by drug acquisition and administration costs. Treatment-related costs increased during later lines of therapy for all countries except France, where they decreased after first-line therapy. Pain control and antiemetics were the most common supportive care medications.

conclusionsThis study provides real-world data on resource utilization and estimated costs in advanced STS and could inform policymakers about treatment burden.

Identifiers

PMID30297977
PMCPMC6157208
OpenAlexW2891673085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.