ArticleScientific reports2018
Multiple intrasyntenic rearrangements and rapid speciation in voles.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Centromeric satellite expansion drives genome evolution in the snowy owl.Genome biology · 2026Article
- Reconstruction of hundreds of reference ancestral genomes across the eukaryotic kingdom.Nature ecology & evolution · 2023Article
- Comparison of detection methods and genome quality when quantifying nuclear mitochondrial insertions in vertebrate genomes.Frontiers in genetics · 2022Article
- Molecular Composition of Heterochromatin and Its Contribution to Chromosome Variation in theGenes · 2021Article
- Intraspecies multiple chromosomal variations including rare tandem fusion in the Russian Far Eastern endemic evoron voleComparative cytogenetics · 2021Article
- Evolutionary rearrangements of X chromosomes in voles (Arvicolinae, Rodentia).Scientific reports · 2020Article
- The molecular genealogy of sequential overlapping inversions implies both homologous chromosomes of a heterokaryotype in an inversion origin.Scientific reports · 2019Article
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Authors and funding
8 authors.
Funding
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Abstract
Remarkably stable genomic chromosome elements (evolutionary conserved segments or syntenies) are the basis of large-scale chromosome architecture in vertebrate species. However, these syntenic elements harbour evolutionary important changes through intrachromosomal rearrangements such as inversions and centromere repositioning. Here, using FISH with a set of 20 region-specific probes on a wide array of 28 species, we analyzed evolution of three conserved syntenic regions of the Arvicolinae ancestral karyotype. Inside these syntenies we uncovered multiple, previously cryptic intrachromosomal rearrangements. Although in each of the three conserved blocks we found inversions and centromere repositions, the blocks experienced different types of rearrangements. In two syntenies centromere repositioning predominated, while in the third region, paracentric inversions were more frequent, whereas pericentric inversions were not detected. We found that some of the intrachromosomal rearrangements, mainly paracentric inversions, were synapomorphic for whole arvicoline genera or tribes: genera Alexandromys and Microtus, tribes Ellobini and Myodini. We hypothesize that intrachromosomal rearrangements within conserved syntenic blocks are a major evolutionary force modulating genome architecture in species-rich and rapidly-evolving rodent taxa. Inversions and centromere repositioning may impact speciation and provide a potential link between genome evolution, speciation, and biogeography.
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