Evidence map›Paper›PMID 30297878›Full record

SynthesisPediatric research2019

Fetal programming of neuropsychiatric disorders by maternal pregnancy depression: a systematic mini review.

Rachel Robinson, Marius Lahti-Pulkkinen, Kati Heinonen, Rebecca M Reynolds, Katri Räikkönen

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Pediatric research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Trial
  2. Article
  3. They will be famous: Multipotent stem cells in breast milk.World journal of clinical pediatrics · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Global Network Organization of the Fetal Functional Connectome.Cerebral cortex (New York, N.Y. : 1991) · 2021
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rachel RobinsonDepartment of Psychology and Logopedics, University of Helsinki, Helsinki, Finland. Rachel.robinson@helsinki.fi.
Marius Lahti-PulkkinenDepartment of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.
Kati HeinonenDepartment of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.
Rebecca M ReynoldsUniversity/British Heart Foundation Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.
Katri RäikkönenDepartment of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMaternal depression complicates a large proportion of pregnancies. Current evidence shows numerous harmful effects on the offspring. Reviews, which include depression, concluded that stress has harmful effects on the offspring's outcomes neuro-cognitive development, temperament traits, and mental disorders.

objectiveThis mini review of recent studies, sought to narrow the scope of exposure and identify studies specifically assessing prenatal depression and offspring neuropsychiatric outcomes. STUDY ELIGIBILITY CRITERIA: The review included longitudinal, cohort, cross-sectional, clinical, quasi-experimental, epidemiological, or intervention study designs published in English from 2014 to 2018.

participantsStudy populations included mother-child dyads, mother-father-child triads, mother-alternative caregiver-child triads, and family studies utilizing sibling comparisons.

methodsWe searched PubMED and Web of Science. Study inclusion and data extraction were based on standardized templates. The quality of evidence was assessed using the Newcastle-Ottawa Scale (NOS).

resultsThirteen studies examining neuropsychiatric outcomes were included. We judged the evidence to be moderate to high quality.

conclusionsOur review supports that maternal prenatal depression is associated with neuropsychiatric adversities in children. IMPLICATIONS: Future investigations should unravel the biological underpinnings and target timely interventions as early in pregnancy as possible to prevent offspring neuropsychiatric harms.

Indexed as

Fetal DevelopmentDepressionFemaleHumansMental DisordersNervous System DiseasesPregnancyPregnancy Complications

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.