ReviewPediatric research2019
Oxygen therapy of the newborn from molecular understanding to clinical practice.
Review in Pediatric research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- European Consensus Guidelines on the Management of Respiratory Distress Syndrome - 2019 Update.Neonatology · 2019Guideline
- Oxidative stress, burnout, National Institutes of Health, work relative value units, and Medicaid: Need for an emergency transfusion.Pediatric research · 2026Review
- Association between 5-minute oxygen saturation and neonatal death and intraventricular hemorrhage among extremely preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2025Article
- Oxygenation of Immature Infants in the Delivery Room and Beyond: A Quest for Future Research.Neonatology · 2025Article
- Apnea of Prematurity and Oxidative Stress: Potential Implications.Antioxidants (Basel, Switzerland) · 2024Review
- Temporal Dynamics of Oxidative Stress and Inflammation in Bronchopulmonary Dysplasia.International journal of molecular sciences · 2024Review
- Delivery Room Oxygen for Preterm Infants-Uncertainty Persists.JAMA pediatrics · 2024Article
- Role of Myeloperoxidase, Oxidative Stress, and Inflammation in Bronchopulmonary Dysplasia.Antioxidants (Basel, Switzerland) · 2024Review
- Hyperoxemia among Pediatric Intensive Care Unit Patients Receiving Oxygen Therapy.Journal of pediatric intensive care · 2024Article
- Prevention of Inflammatory Disorders in the Preterm Neonate: An Update with a Special Focus on Bronchopulmonary Dysplasia.Neonatology · 2024Review
- Oxygen in the neonatal ICU: a complicated history and where are we now?Frontiers in pediatrics · 2024Review
- Neonatal resuscitation with continuous chest compressions and high frequency percussive ventilation in preterm lambs.Pediatric research · 2024Article
- Long Non-Coding RNAs in Hypoxia and Oxidative Stress: Novel Insights Investigating a Piglet Model of Perinatal Asphyxia.Biology · 2023Article
- Respiratory Management of the Preterm Infant: Supporting Evidence-Based Practice at the Bedside.Children (Basel, Switzerland) · 2023Review
- Antenatal and Postnatal Sequelae of Oxidative Stress in Preterm Infants: A Narrative Review Targeting Pathophysiological Mechanisms.Antioxidants (Basel, Switzerland) · 2023Review
- Semi-mechanistic Modeling of Hypoxanthine, Xanthine, and Uric Acid Metabolism in Asphyxiated Neonates.Clinical pharmacokinetics · 2022Article
- Physiology of neonatal resuscitation: Giant strides with small breaths.Seminars in perinatology · 2022Review
- Splanchnic oxygen saturation during reoxygenation with 21% or 100% OPediatric research · 2022Article
- TRAIL protects the immature lung from hyperoxic injury.Cell death & disease · 2022Article
- Pulmonary Resilience: Moderating the Association between Oxygen Exposure and Pulmonary Outcomes in Extremely Preterm Newborns.Neonatology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 4 countries.
Funding
Abstract
Oxygen is one of the most critical components of life. Nature has taken billions of years to develop optimal atmospheric oxygen concentrations for human life, evolving from very low, peaking at 30% before reaching 20.95%. There is now increased understanding of the potential toxicity of both too much and too little oxygen, especially for preterm and asphyxiated infants and of the potential and lifelong impact of oxygen exposure, even for a few minutes after birth. In this review, we discuss the contribution of knowledge gleaned from basic science studies and their implication in the care and outcomes of the human infant within the first few minutes of life and afterwards. We emphasize current knowledge gaps and research that is needed to answer a problem that has taken Nature a considerably longer time to resolve.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.