Evidence map›Paper›PMID 30297838›Full record

ArticleNature communications2018

C

Baharan Fekry, Kristen A Jeffries, Amin Esmaeilniakooshkghazi, Zdzislaw M Szulc, Kevin J Knagge, David R Kirchner, David A Horita, Sergey A Krupenko, Natalia I Krupenko

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 100 citations in OpenAlex.

  1. Determinants of CBiomolecules · 2026
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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Baharan FekryUniversity of North Carolina at Chapel Hill Nutrition Research Institute, Kannapolis, NC 28081, USA.
Kristen A JeffriesUniversity of North Carolina at Chapel Hill Nutrition Research Institute, Kannapolis, NC 28081, USA.
Amin EsmaeilniakooshkghaziUniversity of North Carolina at Chapel Hill Nutrition Research Institute, Kannapolis, NC 28081, USA.
Zdzislaw M SzulcDepartment of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC 29425, USA.
Kevin J KnaggeDavid Murdock Research Institute, Kannapolis, NC 28081, USA.
David R KirchnerDavid Murdock Research Institute, Kannapolis, NC 28081, USA.
David A HoritaUniversity of North Carolina at Chapel Hill Nutrition Research Institute, Kannapolis, NC 28081, USA.ORCID http://orcid.org/0000-0002-9563-107X
Sergey A KrupenkoUniversity of North Carolina at Chapel Hill Nutrition Research Institute, Kannapolis, NC 28081, USA.
Natalia I KrupenkoUniversity of North Carolina at Chapel Hill Nutrition Research Institute, Kannapolis, NC 28081, USA. natalia_krupenko@unc.edu.ORCID http://orcid.org/0000-0003-2977-1557
University of North Carolina at Chapel Hill · USDavid H. Murdock Research Institute · USMedical University of South Carolina · US

Funding

UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Ian Michael Carroll · 1999 to 2026
$31.6M
THE ROLE OF LACTOSYLCERAMIDE IN RENAL AGING AND DISEASEP20RR017677 · NCRR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI CROSSON, CRAIG E. · 2002 to 2011
$23.4M
RESEARCH PILOT PROJECTS PROGRAMP30GM103339 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI CROSSON, CRAIG E. · 2012 to 2016
$5.4M
Ceramide signaling in the regulation of cellular response to folate stressR01CA193782 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KRUPENKO, NATALIA IVANOVNA · 2015 to 2019
$1.7M
NCI NIH HHS R01 CA193782NCRR NIH HHS P20 RR017677NIDDK NIH HHS P30 DK056350NIGMS NIH HHS P30 GM103339U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) CA193782-01
6 · The paper itself

Abstract

Ceramides are important participants of signal transduction, regulating fundamental cellular processes. Here we report the mechanism for activation of p53 tumor suppressor by C

Indexed as

Stress, PhysiologicalA549 CellsActive Transport, Cell NucleusCell NucleusCeramidesHCT116 CellsHeLa CellsHep G2 CellsHumansLigandsPC-3 CellsProtein BindingProto-Oncogene Proteins c-mdm2Tumor Suppressor Protein p53Ubiquitin-Protein LigasesCeramidesLigandsProto-Oncogene Proteins c-mdm2Tumor Suppressor Protein p53Ubiquitin-Protein Ligases

Identifiers

PMID30297838
PMCPMC6175828
OpenAlexW2894800084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.