ArticleScientific reports2018
Gene coexpression network analysis combined with metabonomics reveals the resistance responses to powdery mildew in Tibetan hulless barley.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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29 citing papers in PubMed, 63 citations in OpenAlex.
- Combined transcriptomics and metabolomics reveals the molecular mechanism by which rice responds to Ustilaginoidea virens infection.BMC plant biology · 2026Article
- Unveiling the TGA gene family in Qingke (Hordeum vulgare L. var. nudum) and the role of HvnTGA2 in host-pathogen interaction.BMC plant biology · 2026Article
- A voyage of reprogrammable metabolic bioengineering reshapes plant defense: from editing tools to synthetic systems.Frontiers in plant science · 2026Review
- Dissecting adult plant resistance to stem rust through multi-model GWAS in a diverse barley germplasm panel.Frontiers in plant science · 2025Article
- Spatial and single-cell transcriptomics capture two distinct cell states in soybean defense response toFrontiers in plant science · 2025Article
- Combined metabolome and transcriptome reveal HmF6'H1 regulating simple coumarin accumulation against powdery mildew infection in Heracleum moellendorffii Hance.BMC plant biology · 2024Article
- An Integrated Analysis of Anatomical and Sugar Contents Identifies How Night Temperatures Regulate the Healing Process of Oriental Melon Grafted onto Pumpkin.Plants (Basel, Switzerland) · 2024Article
- Comparative evaluation of physiological and molecular responses of blackcurrant varieties to powdery mildew infection.Frontiers in plant science · 2024Article
- Comparative transcriptome profiling and co-expression network analysis uncover the key genes associated with pear petal defense responses againstFrontiers in plant science · 2024Article
- Coronatine-Induced Maize Defense againstJournal of fungi (Basel, Switzerland) · 2023Article
- Saponarin, a Di-glycosyl Flavone from Barley (ACS omega · 2023Review
- Comparative Transcriptome and Widely Targeted Metabolome Analysis Reveals the Molecular Mechanism of Powdery Mildew Resistance in Tomato.International journal of molecular sciences · 2023Article
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- Virulence and Genetic Types ofJournal of fungi (Basel, Switzerland) · 2023Article
- Identification of key genes involved in secondary metabolite biosynthesis in Digitalis purpurea.PloS one · 2023Article
- Integrated transcriptome and metabolome analysis reveals that flavonoids function in wheat resistance to powdery mildew.Frontiers in plant science · 2023Article
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- Pathogenesis-related protein-4 (PR-4) gene family in Qingke (Hordeum vulgare L. var. nudum): genome-wide identification, structural analysis and expression profile under stresses.Molecular biology reports · 2022Article
- Genome-wide analysis of the Thaumatin-like gene family in Qingke (Frontiers in plant science · 2022Article
- Resistance to Powdery Mildew in Qingke Involves the Accumulation of Aromatic Phenolamides Through Jasmonate-Mediated Activation of Defense-Related Genes.Frontiers in plant science · 2022Article
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8 authors at 1 institution in 1 country.
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Abstract
Powdery mildew is a fungal disease that represents a ubiquitous threat to crop plants. Transcriptomic and metabolomic analyses were used to identify molecular and physiological changes in Tibetan hulless barley in response to powdery mildew. There were 3418 genes and 405 metabolites differentially expressed between the complete resistance cultivar G7 and the sensitive cultivar Z13. Weighted gene coexpression network analysis was carried out, and the differentially expressed genes were enriched in five and four major network modules in G7 and Z13, respectively. Further analyses showed that phytohormones, photosynthesis, phenylpropanoid biosynthesis, and flavonoid biosynthesis pathways were altered during Qingke-Blumeria graminis (DC.) f.sp. hordei (Bgh) interaction. Comparative analyses showed a correspondence between gene expression and metabolite profiles, and the activated defenses resulted in changes of metabolites involved in plant defense response, such as phytohormones, lipids, flavone and flavonoids, phenolamides, and phenylpropanoids. This study enabled the identification of Bgh responsive genes and provided new insights into the dynamic physiological changes that occur in Qingke during response to powdery mildew. These findings greatly improve our understanding of the mechanisms of induced defense response in Qingke and will provide new clues for the development of resistant Tibetan hulless barley varieties.
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