Evidence map›Paper›PMID 30297736›Full record

ArticleScientific reports2018

Probing the origin of matching functional jaws: roles of Dlx5/6 in cranial neural crest cells.

Miki Shimizu, Nicolas Narboux-Nême, Yorick Gitton, Camille de Lombares, Anastasia Fontaine, Gladys Alfama, Taro Kitazawa, Yumiko Kawamura, Eglantine Heude, Lindsey Marshall and 5 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Assessing candidate DLX-regulated genes in the first pharyngeal arch of chick embryos.Developmental dynamics : an official publication of the American Association of Anatomists · 2025
    Article
  2. Article
  3. Loss ofBiomolecules · 2023
    Article
  4. Cells · 2022
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Miki ShimizuDepartment of Physiological Chemistry and Metabolism, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Nicolas Narboux-NêmeEvolution des Régulations Endocriniennes, CNRS, UMR7221, Dept. AVIV, Muséum National d'Histoire Naturelle, Paris, France.ORCID http://orcid.org/0000-0002-3791-7459
Yorick GittonEvolution des Régulations Endocriniennes, CNRS, UMR7221, Dept. AVIV, Muséum National d'Histoire Naturelle, Paris, France.ORCID http://orcid.org/0000-0002-6808-6010
Camille de LombaresEvolution des Régulations Endocriniennes, CNRS, UMR7221, Dept. AVIV, Muséum National d'Histoire Naturelle, Paris, France.
Anastasia FontaineEvolution des Régulations Endocriniennes, CNRS, UMR7221, Dept. AVIV, Muséum National d'Histoire Naturelle, Paris, France.
Gladys AlfamaEvolution des Régulations Endocriniennes, CNRS, UMR7221, Dept. AVIV, Muséum National d'Histoire Naturelle, Paris, France.
Taro KitazawaDepartment of Physiological Chemistry and Metabolism, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Yumiko KawamuraDepartment of Physiological Chemistry and Metabolism, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Eglantine HeudeEvolution des Régulations Endocriniennes, CNRS, UMR7221, Dept. AVIV, Muséum National d'Histoire Naturelle, Paris, France.
Lindsey MarshallEvolution des Régulations Endocriniennes, CNRS, UMR7221, Dept. AVIV, Muséum National d'Histoire Naturelle, Paris, France.
Hiroki HigashiyamaDepartment of Physiological Chemistry and Metabolism, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.ORCID http://orcid.org/0000-0003-1324-8139
Youichiro WadaIsotope Science Center and Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, 153-8904, Japan.
Yukiko KuriharaDepartment of Physiological Chemistry and Metabolism, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Hiroki KuriharaDepartment of Physiological Chemistry and Metabolism, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan. kuri-tky@umin.net.
Giovanni LeviEvolution des Régulations Endocriniennes, CNRS, UMR7221, Dept. AVIV, Muséum National d'Histoire Naturelle, Paris, France. glevi@mnhn.fr.
Centre National de la Recherche Scientifique · FRThe University of Tokyo · JPJapan Science and Technology Agency · JP

Funding

Agence Nationale de la Recherche (French National Research Agency) ANR-17-CE14-0024Agence Nationale de la Recherche (French National Research Agency) ANR-17-CE37-0007European Commission (EC) EU-FP7-HEALTH-602757Japan Science and Technology Agency (JST) JPMJCR13W2JST | Core Research for Evolutional Science and Technology (CREST) JPMJCR13W2Ministry of Education, Culture, Sports, Science, and Technology (MEXT) 15H02536
6 · The paper itself

Abstract

Gnathostome jaws derive from the first pharyngeal arch (PA1), a complex structure constituted by Neural Crest Cells (NCCs), mesodermal, ectodermal and endodermal cells. Here, to determine the regionalized morphogenetic impact of Dlx5/6 expression, we specifically target their inactivation or overexpression to NCCs. NCC-specific Dlx5/6 inactivation (NCC

Indexed as

Gene Expression Regulation, DevelopmentalAnimalsHomeodomain ProteinsMandibleMaxillaMiceMice, Mutant StrainsNeural CrestDlx5 protein, mouseDlx6 protein, mouseHomeodomain Proteins

Identifiers

PMID30297736
PMCPMC6175850
OpenAlexW2952069971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.