Evidence map›Paper›PMID 30297662›Full record

ReviewMedical sciences (Basel, Switzerland)2018

Human Dendritic Cells: Ontogeny and Their Subsets in Health and Disease.

Sandra Georgina Solano-Gálvez, Sonia Margarita Tovar-Torres, María Sofía Tron-Gómez, Ariane Estrella Weiser-Smeke, Diego Abelardo Álvarez-Hernández, Giorgio Alberto Franyuti-Kelly, Mijail Tapia-Moreno, Antonio Ibarra, Laila Gutiérrez-Kobeh, Rosalino Vázquez-López

Open access · goldAbstract readReview
In one paragraph

Review in Medical sciences (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. [Pulmonary innate immune response in Sars-cov-2 infection]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2022
    Pooled it
  2. Article
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  6. Immunomodulatory Effects of PulmonaromPharmaceuticals (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Sandra Georgina Solano-GálvezDepartamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico. solano-sandra@hotmail.com.
Sonia Margarita Tovar-TorresDepartamento de Microbiología, Centro de Investigación en Ciencias de la Salud, Facultad de Ciencias de la Salud (CICSA), Universidad Anáhuac México Campus Norte, Estado de México 52786, Mexico. soniatovart@gmail.com.
María Sofía Tron-GómezDepartamento de Microbiología, Centro de Investigación en Ciencias de la Salud, Facultad de Ciencias de la Salud (CICSA), Universidad Anáhuac México Campus Norte, Estado de México 52786, Mexico. sofia.tron@hotmail.com.
Ariane Estrella Weiser-SmekeDepartamento de Microbiología, Centro de Investigación en Ciencias de la Salud, Facultad de Ciencias de la Salud (CICSA), Universidad Anáhuac México Campus Norte, Estado de México 52786, Mexico. aweisers@gmail.com.
Diego Abelardo Álvarez-HernándezDepartamento de Microbiología, Centro de Investigación en Ciencias de la Salud, Facultad de Ciencias de la Salud (CICSA), Universidad Anáhuac México Campus Norte, Estado de México 52786, Mexico. diego.alvarez.hernandez@hotmail.com.
Giorgio Alberto Franyuti-KellyMedical IMPACT, Infectious Diseases Department, Mexico City 53900, Mexico. giorgio.franyuti@gmail.com.
Mijail Tapia-MorenoMedical IMPACT, Infectious Diseases Department, Mexico City 53900, Mexico. tapkov@hotmail.com.ORCID 0000-0001-7617-9295
Antonio IbarraCoordinación del Centro de Investigación en Ciencias de la Salud, Facultad de Ciencias de la Salud (CICSA), Universidad Anáhuac México Campus Norte, Estado de México 52786, Mexico. jose.ibarra@anahuac.mx.
Laila Gutiérrez-KobehUnidad de Investigación UNAM-INC, División Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México-Instituto Nacional de Cardiología "Ignacio Chávez", Mexico City 14080, Mexico. lgutierr@unam.mx.
Rosalino Vázquez-LópezDepartamento de Microbiología, Centro de Investigación en Ciencias de la Salud, Facultad de Ciencias de la Salud (CICSA), Universidad Anáhuac México Campus Norte, Estado de México 52786, Mexico. vazquezrosalino@yahoo.com.ORCID 0000-0002-1982-7329
Universidad Anáhuac · MXInstituto Nacional de Cardiología · MXUniversidad Nacional Autónoma de México · MX

Funding

CICSA, FCS Universidad Anáhuac México Campus Norte 201638 - CSNBIAVALR170605171
6 · The paper itself

Abstract

Dendritic cells (DCs) are a type of cells derived from bone marrow that represent 1% or less of the total hematopoietic cells of any lymphoid organ or of the total cell count of the blood or epithelia. Dendritic cells comprise a heterogeneous population of cells localized in different tissues where they act as sentinels continuously capturing antigens to present them to T cells. Dendritic cells are uniquely capable of attracting and activating naïve CD4⁺ and CD8⁺ T cells to initiate and modulate primary immune responses. They have the ability to coordinate tolerance or immunity depending on their activation status, which is why they are also considered as the orchestrating cells of the immune response. The purpose of this review is to provide a general overview of the current knowledge on ontogeny and subsets of human dendritic cells as well as their function and different biological roles.

Indexed as

conventional DCs (cDCs)human dendritic cellsmonocyte-derived DCs (moDCs)myeloid DCs (mDCs)ontogenyplasmacytoid DCs (pDCs)subsets

Identifiers

PMID30297662
PMCPMC6313400
OpenAlexW2897246274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.