Evidence map›Paper›PMID 30297656›Full record

ArticleNutrients2018

Salmon Fillet Intake Led to Higher Serum Triacylglycerol in Obese Zucker Fa/Fa Rats But Not in Normolipidemic Long-Evans Rats.

Linn Anja Vikøren, Aslaug Drotningsvik, Svein Are Mjøs, Gunnar Mellgren, Oddrun Anita Gudbrandsen

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Linn Anja VikørenDietary Protein Research Group, Department of Clinical Medicine, University of Bergen, 5020 Bergen, Norway. linn.anja.slake.vikoren@helse-bergen.no.
Aslaug DrotningsvikDietary Protein Research Group, Department of Clinical Medicine, University of Bergen, 5020 Bergen, Norway. aslaug.drotningsvik@uib.no.ORCID 0000-0003-3129-5756
Svein Are MjøsDepartment of Chemistry, University of Bergen, P.O. Box 7803, 5020 Bergen, Norway. svein.mjos@uib.no.ORCID 0000-0002-5948-7373
Gunnar MellgrenDepartment of Clinical Science, KG Jebsen Center for Diabetes Research, University of Bergen, Haukeland University Hospital, 5021 Bergen, Norway. gunnar.mellgren@uib.no.
Oddrun Anita GudbrandsenDietary Protein Research Group, Department of Clinical Medicine, University of Bergen, 5020 Bergen, Norway. nkjgu@uib.no.ORCID 0000-0001-5268-692X
Haukeland University Hospital · NOUniversity of Bergen · NONofima · NO

Funding

Fiskeri - og havbruksnæringens forskningsfond 900842
6 · The paper itself

Abstract

The triacylglycerol lowering effect of fatty fish and fish oils is well recognized, however we recently showed that salmon intake resulted in higher serum triacylglycerol concentration in obese Zucker fa/fa rats. Since effects of salmon fillet have never before been studied in rats, the objective of this study was to compare effects of salmon intake on serum lipids in hyperlipidemic obese rats with normolipidemic lean rats. Zucker fa/fa rats and Long-Evans rats were fed diets with 25% protein from baked salmon fillet and 75% protein from casein, or casein as sole protein source (control group) for four weeks. Serum triacylglycerol concentration was higher, and cholesterol and apolipoproteinB-100 concentrations were lower in Zucker fa/fa rats fed Baked Salmon Diet compared to Zucker fa/fa rats fed Control Diet, with no differences in serum triacylglycerol, cholesterol and apolipoproteinB-100 between Long-Evans rats fed Baked Salmon Diet or Control Diet. Serum triacylglycerol fatty acid composition showed greater similarities to dietary fatty acids in Zucker fa/fa rats than in Long-Evans rats. To conclude, intake of baked salmon fillet resulted in higher serum triacylglycerol concentration and lower serum cholesterol concentration in hyperlipidemic obese Zucker fa/fa rats but did not affect serum lipids in normolipidemic lean Long-Evans rats.

Indexed as

DietFeeding BehaviorSalmonAnimalsApolipoproteins BCholesterolCookingDietary ProteinsFish ProteinsHyperlipidemiasMaleObesityRats, Inbred LECRats, ZuckerReference ValuesSeafoodApolipoproteins BCholesterolDietary ProteinsFish ProteinsTriglyceridesapoB100apoB48fatty acidsfatty fishLong-Evans ratn-3 PUFAphospholipidssalmontriacylglycerolsZucker fa/fa rat

Identifiers

PMID30297656
PMCPMC6213735
OpenAlexW2895255269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.