Evidence map›Paper›PMID 30297526›Full record

ArticleInfection and immunity2019

Jeremy Bechelli, Leoncio Vergara, Claire Smalley, Tetyana P Buzhdygan, Sean Bender, William Zhang, Yan Liu, Vsevolod L Popov, Jin Wang, Nisha Garg and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. ATG9 inhibitsAutophagy · 2025
    Article
  5. Article
  6. Infection and immunity · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Innate immunity in rickettsial infections.Frontiers in cellular and infection microbiology · 2023
    Review
  11. Review
  12. Article
  13. Apoptosis and Autophagy: Current Understanding in Tick-Pathogen Interactions.Frontiers in cellular and infection microbiology · 2022
    Review
  14. Granulomatous mastitis caused by Rickettsia species.Virchows Archiv : an international journal of pathology · 2021
    Article
  15. Pathogens (Basel, Switzerland) · 2021
    Article
  16. Review
  17. Review
  18. Article
  19. Subversion of Host Innate Immunity byFrontiers in immunology · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Jeremy BechelliDepartment of Pathology, University of Texas Medical Branch at Galveston, Galveston, Texas, USA.ORCID 0000-0002-8786-7795
Leoncio VergaraCenter for Biomedical Engineering, University of Texas Medical Branch at Galveston, Galveston, Texas, USA.
Claire SmalleyDepartment of Pathology, University of Texas Medical Branch at Galveston, Galveston, Texas, USA.
Tetyana P BuzhdyganDepartment of Pathology, University of Texas Medical Branch at Galveston, Galveston, Texas, USA.
Sean BenderDepartment of Pathology, University of Texas Medical Branch at Galveston, Galveston, Texas, USA.
William ZhangHigh School Student Summer Research Program, University of Texas Medical Branch at Galveston, Galveston, Texas, USA.
Yan LiuDepartment of Pathology, University of Texas Medical Branch at Galveston, Galveston, Texas, USA.
Vsevolod L PopovDepartment of Pathology, University of Texas Medical Branch at Galveston, Galveston, Texas, USA.
Jin WangImmunobiology and Transplant Science Center, Houston Methodist Research Institute, Houston, Texas, USA.
Nisha GargDepartment of Microbiology and Immunology, University of Texas Medical Branch at Galveston, Galveston, Texas, USA.
Seungmin HwangDepartment of Pathology, University of Chicago, Chicago, Illinois, USA.ORCID 0000-0003-0846-5462
David H WalkerDepartment of Pathology, University of Texas Medical Branch at Galveston, Galveston, Texas, USA.
Rong FangDepartment of Pathology, University of Texas Medical Branch at Galveston, Galveston, Texas, USA rofang@utmb.edu.
The University of Texas Medical Branch at Galveston · USHouston Methodist · USSam Houston State University · USUniversity of Chicago · US

Funding

Biodefense Training ProgramT32AI060549 · NIAID · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI ASHOK K CHOPRA, Janice J Endsley · 2004 to 2026
$3.0M
Molecular Regulation of Long-term Immune MemoryR01AI123221 · NIAID · METHODIST HOSPITAL RESEARCH INSTITUTE · PI WANG, JIN · 2016 to 2020
$2.0M
Activation and in vivo Functions of Initiator CaspasesR01AI056210 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI WANG, JIN · 2003 to 2007
$1.5M
Mechanisms by which rickettsiae increase microvascular permeabilityR21AI133359 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI FANG, RONG MEGAN · 2018 to 2019
$434k
Mechanisms of Cytosolic Clearance of RickettsiaeR21AI101413 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI FANG, RONG MEGAN · 2014 to 2015
$426k
NIAID NIH HHS R01 AI056210NIAID NIH HHS R01 AI123221NIAID NIH HHS R21 AI101413NIAID NIH HHS R21 AI133359NIAID NIH HHS T32 AI060549
6 · The paper itself

Abstract

Rickettsiae can cause life-threatening infections in humans. Macrophages are one of the initial targets for rickettsiae after inoculation by ticks. However, it remains poorly understood how rickettsiae remain free in macrophages prior to establishing their infection in microvascular endothelial cells. Here, we demonstrated that the concentration of

Indexed as

Host-Pathogen InteractionsAnimalsAutophagy-Related Protein 5Cells, CulturedFemaleInterleukin-1betaMacrophagesMice, Inbred C57BLRickettsiaSpotted Fever Group RickettsiosisAtg5 protein, mouseAutophagy-Related Protein 5Interleukin-1betaAtg5autophagosomesIL-1βmouse macrophagesRickettsia australis

Identifiers

PMID30297526
PMCPMC6300621
OpenAlexW2905167154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.