Evidence map›Paper›PMID 30297418›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

DSCAM promotes self-avoidance in the developing mouse retina by masking the functions of cadherin superfamily members.

Andrew M Garrett, Andre Khalil, David O Walton, Robert W Burgess

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Genetic Deletion of Sarm1 in Mouse Models of Three Neurological Diseases.Journal of the peripheral nervous system : JPNS · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. bioRxiv : the preprint server for biology · 2023
    Article
  13. Article
  14. Review
  15. Article
  16. Structure of cell-cell adhesion mediated by the Down syndrome cell adhesion molecule.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  17. Review
  18. Review
  19. Review
  20. Molecular mechanisms regulating synaptic specificity and retinal circuit formation.Wiley interdisciplinary reviews. Developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Andrew M GarrettThe Jackson Laboratory, Bar Harbor, ME 04609.
Andre KhalilCompuMAINE Laboratory, Department of Biomedical Engineering, University of Maine, Orono, ME 04469.ORCID 0000-0001-6020-2665
David O WaltonThe Jackson Laboratory, Bar Harbor, ME 04609.
Robert W BurgessThe Jackson Laboratory, Bar Harbor, ME 04609; robert.burgess@jax.org.
Jackson Laboratory · USUniversity of Maine · US

Funding

Shared Resource ManagementP30CA034196 · NCI · JACKSON LABORATORY · PI Paul Robson · 1985 to 2026
$61.9M
Genetics of the Neuromuscular Junction: Mechanisms and Disease ModelsR01NS054154 · NINDS · JACKSON LABORATORY · PI BURGESS, ROBERT W. · 2006 to 2019
$6.0M
REPRODUCTIVE BIOLOGYT32HD007065 · NICHD · JACKSON LABORATORY · PI BRAUN, ROBERT E · 1985 to 2020
$2.6M
Intracellular signaling by DSCAM during retinal developmentF32EY021942 · NEI · JACKSON LABORATORY · PI GARRETT, ANDREW · 2011 to 2012
$87k
NCI NIH HHS P30 CA034196NEI NIH HHS F32 EY021942NICHD NIH HHS T32 HD007065NINDS NIH HHS R01 NS054154
6 · The paper itself

Abstract

During neural development, self-avoidance ensures that a neuron's processes arborize to evenly fill a particular spatial domain. At the individual cell level, self-avoidance is promoted by genes encoding cell-surface molecules capable of generating thousands of diverse isoforms, such as

Indexed as

AnimalsCadherinsCell AdhesionCell Adhesion MoleculesCell LineCell MembraneChoice BehaviorDrosophilaDrosophila ProteinsHEK293 CellsHumansMiceNeural Cell Adhesion MoleculesNeuritesNeurogenesisNeuronsCadherinsCell Adhesion MoleculesDrosophila ProteinsDscam protein, mouseNeural Cell Adhesion Moleculesautismcadherinscell identitydendrite fasciculationDSCAMs

Identifiers

PMID30297418
PMCPMC6205498
OpenAlexW2896732614

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.