Evidence map›Paper›PMID 30297364›Full record

ArticleAntimicrobial agents and chemotherapy2018

Two Regulators, PA3898 and PA2100, Modulate the Pseudomonas aeruginosa Multidrug Resistance MexAB-OprM and EmrAB Efflux Pumps and Biofilm Formation.

Yun Heacock-Kang, Zhenxin Sun, Jan Zarzycki-Siek, Kanchana Poonsuk, Ian A McMillan, Rungtip Chuanchuen, Tung T Hoang

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Infection and immunity · 2023
    Review
  8. Review
  9. Efflux, Signaling and Warfare in a Polymicrobial World.Antibiotics (Basel, Switzerland) · 2023
    Review
  10. Article
  11. Article
  12. Activity ofMicrobiology spectrum · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Yun Heacock-KangDepartment of Microbiology, University of Hawaii at Manoa, Honolulu, Hawaii, USA.ORCID 0000-0002-7304-9687
Zhenxin SunDepartment of Microbiology, University of Hawaii at Manoa, Honolulu, Hawaii, USA.ORCID 0000-0003-3452-3881
Jan Zarzycki-SiekDepartment of Microbiology, University of Hawaii at Manoa, Honolulu, Hawaii, USA.
Kanchana PoonsukDepartment of Veterinary Public Health, Chulalongkorn University, Bangkok, Thailand.
Ian A McMillanDepartment of Microbiology, University of Hawaii at Manoa, Honolulu, Hawaii, USA.
Rungtip ChuanchuenDepartment of Veterinary Public Health, Chulalongkorn University, Bangkok, Thailand.
Tung T HoangDepartment of Microbiology, University of Hawaii at Manoa, Honolulu, Hawaii, USA tongh@hawaii.edu.
University of Hawaiʻi at Mānoa · USChulalongkorn University · TH

Funding

Functional Genomics of Single- and Mixed-Species Biofilms in Spatiotemporal ScaleR01GM103580 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI HOANG, TUNG T · 2013 to 2016
$1.0M
Functional Characterization of Essential Burkholderia pseudomallei Virulence RegulatorsR21AI123913 · NIAID · UNIVERSITY OF HAWAII AT MANOA · PI HOANG, TUNG T · 2016 to 2017
$389k
NIAID NIH HHS R21 AI123913NIGMS NIH HHS R01 GM103580
6 · The paper itself

Abstract

It is generally believed that the

Indexed as

AnimalsBacterial Outer Membrane ProteinsBacterial ProteinsBinding SitesBiofilmsDrosophila melanogasterGene Expression Regulation, BacterialMaleMembrane ProteinsMembrane Transport ProteinsMice, Inbred BALB CMicrobial Sensitivity TestsMutationPhenazinesPseudomonas aeruginosaPseudomonas InfectionsBacterial Outer Membrane ProteinsBacterial ProteinsemrA protein, BacteriaMembrane ProteinsMembrane Transport ProteinsMexA protein, Pseudomonas aeruginosaMexB protein, Pseudomonas aeruginosaMexR protein, Pseudomonas aeruginosaOprM protein, Pseudomonas aeruginosaphenazinePhenazinesRepressor ProteinsEmrABMexAB-OprMPA2100PA3898phenazinePseudomonas aeruginosa

Identifiers

PMID30297364
PMCPMC6256797
OpenAlexW2894802948

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.