Evidence map›Paper›PMID 30297357›Full record

ArticleJournal of bacteriology2018

Thermal and Nutritional Regulation of Ribosome Hibernation in Staphylococcus aureus.

Arnab Basu, Kathryn E Shields, Christopher S Eickhoff, Daniel F Hoft, M N Yap

Open access · hybridAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Structural insights into RNA recognition by theProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
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  5. Article
  6. Article
  7. Article
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  9. Bidirectional sequestration between a bacterial hibernation factor and a glutamate metabolizing protein.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  10. Article
  11. Article
  12. Progression from remodeling to hibernation of ribosomes in zinc-starved mycobacteria.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  13. Revealing 29 sets of independently modulated genes inProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Arnab BasuEdward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, Missouri, USA.
Kathryn E ShieldsEdward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, Missouri, USA.
Christopher S EickhoffDivision of Infectious Diseases, Allergy and Immunology, Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, Missouri, USA.
Daniel F HoftDivision of Infectious Diseases, Allergy and Immunology, Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, Missouri, USA.
M N YapEdward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, Missouri, USA meengan.yap@health.slu.edu.ORCID 0000-0003-4213-4050
Saint Louis University · US

Funding

Regulation and function of bacterial hibernating 100S ribosomeR01GM121359 · NIGMS · SAINT LOUIS UNIVERSITY · PI YAP, M.-N. FRANCES · 2017 to 2025
$3.2M
NIGMS NIH HHS R01 GM121359
6 · The paper itself

Abstract

The translationally silent 100S ribosome is a poorly understood form of the dimeric 70S complex that is ubiquitously found in all bacterial phyla. The elimination of the hibernating 100S ribosome leads to translational derepression, ribosome instability, antibiotic sensitivity, and biofilm defects in some bacteria. In

Indexed as

Bacterial ProteinsDimerizationEpistasis, GeneticGene Expression Regulation, BacterialProtein BiosynthesisRepressor ProteinsRibosomal ProteinsSigma FactorStaphylococcus aureusBacterial ProteinsCodY protein, Staphylococcus aureusHPF protein, Staphylococcus aureusRepressor ProteinsRibosomal ProteinsSigB protein, BacteriaSigma FactorCodYgeneral stress responseHflXhibernationHPFribosome

Identifiers

PMID30297357
PMCPMC6256015
OpenAlexW2896933546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.