Evidence map›Paper›PMID 30297132›Full record

ArticleBiophysical journal2018

A Plugin Framework for Extending the Simulation Capabilities of FEBio.

Steve A Maas, Steven A LaBelle, Gerard A Ateshian, Jeffrey A Weiss

Abstract read
In one paragraph

Article in Biophysical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  16. Tools for computational analysis of moving boundary problems in cellular mechanobiology.Wiley interdisciplinary reviews. Systems biology and medicine · 2020
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Steve A MaasDepartment of Biomedical Engineering, and Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, Utah.
Steven A LaBelleDepartment of Biomedical Engineering, and Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, Utah.
Gerard A AteshianDepartment of Mechanical Engineering, Columbia University, New York, New York.
Jeffrey A WeissDepartment of Biomedical Engineering, and Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, Utah. Electronic address: jeff.weiss@utah.edu.

Funding

Finite Elements For Biomechanics And BiophysicsR01GM083925 · NIGMS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI GERARD A. ATESHIAN, JEFFREY A. WEISS · 2008 to 2026
$7.6M
Regenerative Rehabilitation of Complex Musculoskeletal InjuriesR01AR069297 · NIAMS · UNIVERSITY OF OREGON · PI ROBERT E Guldberg · 2016 to 2026
$5.6M
Open Knee(s): Virtual Biomechanical Representations of the Knee JointR01GM104139 · NIGMS · CLEVELAND CLINIC LERNER COM-CWRU · PI ERDEMIR, AHMET · 2013 to 2016
$2.1M
Neovessel Guidance in AngiogenesisR01HL131856 · NHLBI · UNIVERSITY OF UTAH · PI HOYING, JAMES B, WEISS, JEFFREY A. · 2017 to 2020
$1.8M
Computational Framework for Multiscale Mechanics of Connective TissuesR01EB015133 · NIBIB · UNIVERSITY OF UTAH · PI WEISS, JEFFREY A. · 2012 to 2015
$1.0M
NHLBI NIH HHS R01 HL131856NIAMS NIH HHS R01 AR069297NIBIB NIH HHS R01 EB015133NIGMS NIH HHS R01 GM083925NIGMS NIH HHS R01 GM104139
6 · The paper itself

Abstract

The FEBio software suite is a set of software tools for nonlinear finite element analysis in biomechanics and biophysics. FEBio employs mixture theory to account for the multiconstituent nature of biological materials, integrating the field equations for irreversible thermodynamics, solid mechanics, fluid mechanics, mass transport with reactive species, and electrokinetics. This communication describes the development and application of a new "plugin" framework for FEBio. Plugins are dynamically linked libraries that allow users to add new features and to couple FEBio with other domain-specific software applications without modifying the source code directly. The governing equations and simulation capabilities of FEBio are reviewed. The implementation, structure, use, and application of the plugin framework are detailed. Several example plugins are described in detail to illustrate how plugins enrich, extend, and leverage existing capabilities in FEBio, including applications to deformable image registration, constitutive modeling of biological tissues, coupling to an external software package that simulates angiogenesis using a discrete computational model, and a nonlinear reaction-diffusion solver. The plugin feature facilitates dissemination of new simulation methods, reproduction of published results, and coupling of FEBio with other domain-specific simulation approaches such as compartmental modeling, agent-based modeling, and rigid-body dynamics. We anticipate that the new plugin framework will greatly expand the range of applications for the FEBio software suite and thus its impact.

Indexed as

Finite Element AnalysisSoftwareNonlinear Dynamics

Identifiers

PMID30297132
PMCPMC6225080

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.